{
  "abstract": "Randomised trials of vitamin D supplementation for cardiovascular disease and all-cause mortality have generally reported null findings. However, generalisability of results to individuals with low vitamin D status is unclear. We aimed to characterise dose-response relationships between 25-hydroxyvitamin D (25[OH]D) concentrations and risk of coronary heart disease, stroke, and all-cause mortality in observational and Mendelian randomisation frameworks.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 86,
  "authors": [
    {
      "name": "Eleni Sofianopoulou"
    },
    {
      "name": "Stephen Kaptoge"
    },
    {
      "name": "Shoaib Afzal"
    },
    {
      "name": "Tao Jiang"
    },
    {
      "name": "Dipender Gill"
    },
    {
      "name": "Thomas Gundersen"
    },
    {
      "name": "Thomas Bolton"
    },
    {
      "name": "Elias Allara"
    },
    {
      "name": "Matthew Arnold"
    },
    {
      "name": "Amy Mason"
    },
    {
      "name": "Ryan Chung"
    },
    {
      "name": "Lisa Pennells"
    },
    {
      "name": "Fanchao Shi"
    },
    {
      "name": "Luanluan Sun"
    },
    {
      "name": "Peter Willeit"
    },
    {
      "name": "Nita Forouhi"
    },
    {
      "name": "Claudia Langenberg"
    },
    {
      "name": "Stephen Sharp"
    },
    {
      "name": "Salvatore Panico"
    },
    {
      "name": "Gunnar Engström"
    },
    {
      "name": "Olle Melander"
    },
    {
      "name": "Tammy Tong"
    },
    {
      "name": "Aurora Perez-Cornago"
    },
    {
      "name": "Margareta Norberg"
    },
    {
      "name": "Ingegerd Johansson"
    },
    {
      "name": "Verena Katzke"
    },
    {
      "name": "Bernard Srour"
    },
    {
      "name": "María José Sánchez"
    },
    {
      "name": "Daniel Redondo-Sánchez"
    },
    {
      "name": "Anja Olsen"
    },
    {
      "name": "Christina Dahm"
    },
    {
      "name": "Kim Overvad"
    },
    {
      "name": "Magritt Brustad"
    },
    {
      "name": "Guri Skeie"
    },
    {
      "name": "Conchi Moreno-Iribas"
    },
    {
      "name": "N Charlotte Onland-Moret"
    },
    {
      "name": "Yvonne van der Schouw"
    },
    {
      "name": "Konstantinos Tsilidis"
    },
    {
      "name": "Alicia Heath"
    },
    {
      "name": "Claudia Agnoli"
    },
    {
      "name": "Vittorio Krogh"
    },
    {
      "name": "Ian de Boer"
    },
    {
      "name": "Camilla Jannie Kobylecki"
    },
    {
      "name": "Yunus Çolak"
    },
    {
      "name": "Armin Zittermann"
    },
    {
      "name": "Johan Sundström"
    },
    {
      "name": "Paul Welsh"
    },
    {
      "name": "Elisabete Weiderpass"
    },
    {
      "name": "Elom Aglago"
    },
    {
      "name": "Pietro Ferrari"
    },
    {
      "name": "Robert Clarke"
    },
    {
      "name": "Marie-Christine Boutron"
    },
    {
      "name": "Gianluca Severi"
    },
    {
      "name": "Conor Macdonald"
    },
    {
      "name": "Rui Providencia"
    },
    {
      "name": "Giovanna Masala"
    },
    {
      "name": "Raul Zamora Ros"
    },
    {
      "name": "Jolanda Boer"
    },
    {
      "name": "Wm Monique Verschuren"
    },
    {
      "name": "Peggy Cawthon"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/f64j00x8yqcx1.bib",
  "cited_by": 79,
  "doi": "10.1016/s2213-8587(23)00287-5",
  "fulltext_url": null,
  "id": "f64j00x8yqcx1",
  "issns": [
    "2213-8587",
    "2213-8595"
  ],
  "landing_url": "https://hal.inrae.fr/hal-05630940v1",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.sdv"
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    [
      "hal",
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    [
      "openalex",
      "2734|Vitamin D Research Studies"
    ]
  ],
  "openalex": "W4389229411",
  "pdf_url": "https://hal.inrae.fr/hal-05630940/document",
  "pmcid": null,
  "pmid": "38048800",
  "published": "2026-09-03",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/f64j00x8yqcx1.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:27Z",
      "native_id": "hal-05630940",
      "source": "hal",
      "url": "https://hal.inrae.fr/hal-05630940v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "hal:0.sdv",
      "subfield": "general"
    },
    {
      "field": "medicine",
      "origin": "hal:1.sdv.spee",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses",
  "title_text": "Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:27Z",
  "url": "https://research.draconitic.com/paper/f64j00x8yqcx1",
  "venue": "The Lancet. Diabetes & Endocrinology",
  "versions": []
}