{
  "abstract": "Soil salinization is a growing global threat that limits crop productivity. To cope with sodium (Na+) stress, plants have evolved tolerance mechanisms, including excluding Na+ from shoot tissues and tolerating elevated Na+ within shoots through tissue- and cellular-level mechanisms. Most current knowledge of Na+ accumulation comes from organ- or whole-plant measurements that lack the spatial resolution needed to resolve cellular tolerance mechanisms. Here, we used histological approaches to map leaf Na+ distribution in tomato (Solanum) species with contrasting salt-tolerance strategies. In the moderately salt-tolerant, Na+-excluding domesticated tomato (cv. M82), Na+ was largely confined to the bundle sheath, whereas in salt-tolerant, Na+-including wild relatives, Na+ accumulated throughout the blade mesophyll. Consistent with these cell population-specific Na+ patterns, M82, but not Solanum pennellii, exhibited reduced symplastic transport and plasmodesma permeability under salt stress. A genetic screen combined with transcriptome profiling implicated Plasmodesmata-Located Protein 1 (PDLP1), a regulator of callose-mediated plasmodesma closure, in establishing symplastic domains in M82 that restrict Na+ movement into the mesophyll. Moreover, PDLP1 expression was negatively correlated with mesophyll Na+ levels across wild and domesticated tomatoes. Collectively, these results link cellular Na+ enrichment patterns to symplastic connectivity and suggest that PDLP1-mediated regulation of plasmodesmata contributes to leaf-level salt-tolerance strategies.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "name": "Lidor Shaar-Moshe",
      "orcid": "0000-0002-4256-255X"
    },
    {
      "name": "Daniel E Runcie",
      "orcid": "0000-0002-3008-9312"
    },
    {
      "name": "Siobhán M Brady",
      "orcid": "0000-0001-9424-8055"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/f85sxz80zhfqj.bib",
  "cited_by": 1,
  "doi": "10.1093/plphys/kiag779",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13738211/",
  "id": "f85sxz80zhfqj",
  "issns": [
    "0032-0889",
    "1532-2548"
  ],
  "landing_url": "https://doi.org/10.1093/plphys/kiag779",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "AcademicSubjects/SCI01210"
    ],
    [
      "heading",
      "Genomics and Evolution"
    ],
    [
      "heading",
      "Research Article"
    ],
    [
      "openalex",
      "1110|Plant Stress Responses and Tolerance"
    ]
  ],
  "openalex": "W7142659112",
  "pdf_url": "https://academic.oup.com/plphys/advance-article-pdf/doi/10.1093/plphys/kiag779/73033200/kiag779.pdf",
  "pmcid": "PMC13738211",
  "pmid": "42981184",
  "published": "2026-11-04",
  "publisher": "Oxford University Press",
  "ris": "https://research.draconitic.com/paper/f85sxz80zhfqj.ris",
  "sources": [
    {
      "first_seen": "2026-11-09T12:23:14Z",
      "native_id": "PMC13738211",
      "source": "pmc",
      "url": "https://doi.org/10.1093/plphys/kiag779"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:1110|Plant Stress Responses and Tolerance",
      "subfield": "plant-biology"
    }
  ],
  "title": "Tissue-specific accumulation of Na+ in leaves of 2 tomato species is linked to differences in symplastic transport",
  "title_text": "Tissue-specific accumulation of Na+ in leaves of 2 tomato species is linked to differences in symplastic transport",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T12:23:14Z",
  "url": "https://research.draconitic.com/paper/f85sxz80zhfqj",
  "venue": "Plant Physiology",
  "versions": []
}