{
  "abstract": "Coffee consumption is increasing yearly, and so is the quantity of spent coffee grounds, a by-product that still contains bioactive compounds. The goal of this work is to evaluate the lipid fractions (LFs) and polyphenolic fractions (PFs) from roasted coffee grounds (RCG; two varieties of Ugandan origin: Arabica and Robusta) and from the corresponding spent coffee grounds (SCG) extracted with solvents of opposite polarities. A qualitative and quantitative analysis of the extracts was performed using GC-FID, 1H-NMR, Folin–Ciocalteu, HPLC-PDA, DPPH and antibacterial activity methods. A high-quality LF, coffee oil (91.82 g triacylglycerides/100 g LF, 49.85 mol% saturated fatty acids and 50.15 mol% unsaturated fatty acid chains, 8.98 mg GAE/g LF, 20.91% DPPH inhibition), with high extraction yield (10.34 g/100 g SCG), can be recovered from SCG of the Ugandan Arabica variety. In addition, SCG of both Ugandan Arabica and Robusta varieties are promising resources for the recovery of high-quality PF (12.30 and 7.85 mg GAE/g PF, 0.684 and 0.837 mg/g PF chlorogenic acids, 85.17% and 73.95% DPPH inhibition) with good extraction yields (9.35 and 5.63 g/100 g SCG) and with antimicrobial activities that remain after the coffee brewing step. These results highlight SCG of Ugandan origin as a promising resource of bioactive compounds for further valorization.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Chemical and Biochemical Engineering, National University of Science and Technology POLITEHNICA Bucharest, 1, Gh. Polizu Street, Building A, Room A056, RO-011061 Bucharest, Romania",
    "Doctoral School Chemical Engineering and Biotechnologies, National University of Science and Technology POLITEHNICA Bucharest, RO-011061 Bucharest, Romania"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Mihaela Dinu",
      "orcid": "0000-0002-2623-2366"
    },
    {
      "affs": [
        1
      ],
      "name": "Auras Marius Dumitru",
      "orcid": "0009-0009-1970-874X"
    },
    {
      "affs": [
        0
      ],
      "name": "Ana-Maria Claudia Brezoiu",
      "orcid": "0000-0003-4373-295X"
    },
    {
      "affs": [
        0
      ],
      "name": "Gabriela Olimpia Isopencu",
      "orcid": "0000-0002-0763-540X"
    },
    {
      "affs": [
        0
      ],
      "name": "Petrica Iancu"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/f8ep48k3nsexx.bib",
  "cited_by": 0,
  "doi": "10.3390/ijms27219906",
  "fulltext_url": null,
  "id": "f8ep48k3nsexx",
  "issns": [
    "1422-0067"
  ],
  "landing_url": "https://www.mdpi.com/1422-0067/27/21/9906",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [],
  "openalex": null,
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-11-05",
  "publisher": "MDPI AG",
  "ris": "https://research.draconitic.com/paper/f8ep48k3nsexx.ris",
  "sources": [
    {
      "first_seen": "2026-11-06T00:21:14Z",
      "native_id": "10.3390/ijms27219906",
      "source": "crossref",
      "url": "https://www.mdpi.com/1422-0067/27/21/9906"
    }
  ],
  "subjects": [
    {
      "field": "biochemistry",
      "origin": "issn:1422-0067",
      "subfield": "general"
    }
  ],
  "title": "Comparative Study on Coffee and Spent Coffee Grounds of Arabica and Robusta Varieties of Ugandan Origin: Bioactive Properties of Extracts as Circular Resources",
  "title_text": "Comparative Study on Coffee and Spent Coffee Grounds of Arabica and Robusta Varieties of Ugandan Origin: Bioactive Properties of Extracts as Circular Resources",
  "type": "peer-reviewed",
  "updated_at": "2026-11-07T00:21:12Z",
  "url": "https://research.draconitic.com/paper/f8ep48k3nsexx",
  "venue": "International Journal of Molecular Sciences",
  "versions": []
}