{
  "abstract": "Background\n\nSoil salinity is a major constraint to wheat productivity, necessitating the identification of robust genetic loci for breeding. This study aims to dissect the genetic architecture of adult-plant salinity tolerance in a diverse panel of 298 Iranian wheat accessions. A multi-model GWAS framework (MLM, FarmCPU, and BLINK) was deployed under moderate (6 dS/m) and severe (12 dS/m) salinity stress. High-confidence consensus marker-trait associations (MTAs) were validated through comparative synteny analysis with the rice genome. Furthermore, the genomic predictive ability of gBLUP was evaluated across stress regimes.Results\n\nWe identified 45 consensus MTAs, revealing a dynamic \"Genetic Handoff\": constitutive growth-promoting loci predominated under moderate stress, while adaptive ion-homeostasis and \"escape\" loci emerged under severe stress. A major biomass-associated locus on chromosome 5B (TraesCS5B02G000100) was identified as a strict 1:1 ortholog to rice Os12g0641400 (83.53% identity), indicating high evolutionary conservation of sucrose partitioning. Under severe stress, genomic prediction accuracies for K⁺/Na⁺ ratio surged to 0.65, although yield prediction declined due to non-additive effects.Conclusion\n\nOur findings advocate for a Haplotype-Informed Genomic Selection strategy, combining MAS for conserved high-effect loci like TaSUC4 with GS for polygenic backgrounds. This integrated approach provides a robust roadmap for developing salinity-resilient wheat cultivars.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Agronomy and Plant Breeding, Faculty of Agriculture, University of Tehran, Karaj, Iran.",
    "Department of Agronomy and Plant Breeding, Faculty of Agriculture, University of Tehran, Karaj, Iran. mrghanad@ut.ac.ir.",
    "Crop and Horticultural Science Research Department, Agricultural Research, Education and Extension Organization (AREEO), Isfahan Agricultural and Natural Resources Research and Education Center, Isfahan, Iran."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Sayed Mujtaba Sadaat",
      "orcid": "0009-0003-8229-3088"
    },
    {
      "affs": [
        1
      ],
      "name": "Mohammadreza Bihamta",
      "orcid": "0000-0003-0614-0963"
    },
    {
      "affs": [
        0
      ],
      "name": "Valiollah Mohammadi",
      "orcid": "0000-0001-6487-0740"
    },
    {
      "affs": [
        2
      ],
      "name": "Mehrdad Mahlooji",
      "orcid": "0000-0003-0281-5388"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/fczqgypby0y59.bib",
  "cited_by": 0,
  "doi": "10.1186/s12870-026-09622-3",
  "fulltext_url": "https://europepmc.org/articles/PMC13685093",
  "id": "fczqgypby0y59",
  "issns": [
    "1471-2229"
  ],
  "landing_url": "https://europepmc.org/article/MED/42907756",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "QK1-989"
    ],
    [
      "openalex",
      "1110|Wheat and Barley Genetics and Pathology"
    ]
  ],
  "openalex": "W7171319903",
  "pdf_url": "https://europepmc.org/articles/PMC13685093?pdf=render",
  "pmcid": "PMC13685093",
  "pmid": "42907756",
  "published": "2026-07-01",
  "publisher": "BMC",
  "ris": "https://research.draconitic.com/paper/fczqgypby0y59.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:57Z",
      "native_id": "MED:42907756",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42907756"
    },
    {
      "first_seen": "2026-10-30T13:45:44Z",
      "native_id": "54963962256345ec879a41ae1e9f5d5b",
      "source": "doaj",
      "url": "https://doi.org/10.1186/s12870-026-09622-3"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:1110|Wheat and Barley Genetics and Pathology",
      "subfield": "plant-biology"
    }
  ],
  "title": "Deciphering the dynamic genetic architecture of adult-plant salinity tolerance in bread wheat using multi-model GWAS and genomic prediction.",
  "title_text": "Deciphering the dynamic genetic architecture of adult-plant salinity tolerance in bread wheat using multi-model GWAS and genomic prediction.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:45:44Z",
  "url": "https://research.draconitic.com/paper/fczqgypby0y59",
  "venue": "BMC plant biology",
  "versions": []
}