{
  "abstract": "Sex differences in motor unit (MU) properties to simulated microgravity are unknown. Young males and females completed a 21-day head-down bed rest followed by a 21-day retraining. Bed rest reduced knee extensor strength and volume without sex differences. MU firing rate decreased in both groups, more in females, alongside increased serum C-terminal agrin fragment. After retraining, these measures returned to baseline, whereas strength only partially recovered, remaining below baseline.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Biomedical Sciences, University of Padova, Padova, Italy"
  ],
  "article_type": "New results",
  "arxiv": null,
  "author_total": 13,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "F. Sarto"
    },
    {
      "name": "M. Kalc"
    },
    {
      "name": "O. Caputo"
    },
    {
      "name": "K. Pus"
    },
    {
      "name": "R. Magris"
    },
    {
      "name": "G. Martino"
    },
    {
      "name": "C. M. Brusco"
    },
    {
      "name": "M. V. Franchi"
    },
    {
      "name": "G. De Vito"
    },
    {
      "name": "F. Ferranti"
    },
    {
      "name": "B. Simunic"
    },
    {
      "name": "R. Pisot"
    },
    {
      "name": "M. V. Narici"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/fe88d9gqn5h5n.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.11.04.764387",
  "fulltext_url": "https://www.biorxiv.org/content/10.64898/2026.11.04.764387v1.full",
  "id": "fe88d9gqn5h5n",
  "issns": [],
  "landing_url": "https://www.biorxiv.org/content/10.64898/2026.11.04.764387v1",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "biorxiv",
      "physiology"
    ]
  ],
  "openalex": null,
  "pdf_url": "https://www.biorxiv.org/content/10.64898/2026.11.04.764387v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-11-04",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/fe88d9gqn5h5n.ris",
  "sources": [
    {
      "first_seen": "2026-11-06T12:21:02Z",
      "native_id": "10.64898/2026.11.04.764387",
      "source": "biorxiv",
      "url": "https://www.biorxiv.org/content/10.64898/2026.11.04.764387v1"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "biorxiv:physiology",
      "subfield": "physiology"
    }
  ],
  "title": "Responses of Muscle Volume, Strength, and Motor Unit Properties to Bed Rest and Retraining in Young Males and Females",
  "title_text": "Responses of Muscle Volume, Strength, and Motor Unit Properties to Bed Rest and Retraining in Young Males and Females",
  "type": "preprint",
  "updated_at": "2026-11-08T00:21:00Z",
  "url": "https://research.draconitic.com/paper/fe88d9gqn5h5n",
  "venue": "bioRxiv",
  "versions": []
}