{
  "abstract": "A multi-branched fluorogenic probe for the rapid and specific detection of Gram-negative bacteria is reported. Three Gram-negative-targeting azido-modified polymyxins were clicked onto a trivalent scaffold functionalised with the environmental green-emitting fluorophore 7-nitrobenz-2-oxa-1,3-diazole. The probe allowed wash-free detection of target bacteria with increased sensitivity and lower limits of detection compared to monovalent probes.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "name": "Richa Sharma"
    },
    {
      "name": "Maria Rodriguez-Rios"
    },
    {
      "name": "James Crossland"
    },
    {
      "name": "Maulida Septiyana"
    },
    {
      "name": "Alicia Megia-Fernandez"
    },
    {
      "name": "Maxime Klausen"
    },
    {
      "name": "Mark Bradley"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/fjvvj74wk4yvk.bib",
  "cited_by": 3,
  "doi": "10.1039/d4tb01786b",
  "fulltext_url": null,
  "id": "fjvvj74wk4yvk",
  "issns": [
    "2050-750X"
  ],
  "landing_url": "https://hal.science/hal-05747163v1",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.chim"
    ],
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      "hal",
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    ],
    [
      "openalex",
      "1605|Antimicrobial agents and applications"
    ]
  ],
  "openalex": "W4405463784",
  "pdf_url": "https://pubs.rsc.org/en/content/articlepdf/2025/tb/d4tb01786b",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-11",
  "publisher": "Royal Society of Chemistry",
  "ris": "https://research.draconitic.com/paper/fjvvj74wk4yvk.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:34Z",
      "native_id": "hal-05747163",
      "source": "hal",
      "url": "https://hal.science/hal-05747163v1"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1605|Antimicrobial agents and applications",
      "subfield": "organic"
    }
  ],
  "title": "A multi-valent polymyxin-based fluorescent probe for the detection of Gram-negative infections",
  "title_text": "A multi-valent polymyxin-based fluorescent probe for the detection of Gram-negative infections",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:34Z",
  "url": "https://research.draconitic.com/paper/fjvvj74wk4yvk",
  "venue": "Journal of materials chemistry‎ B",
  "versions": []
}