{
  "abstract": "Gross extraction yield alone cannot establish product conformity or broader economic and environmental performance. This critical integrative review examines evidence linking laboratory findings to industrially relevant claims for plant-derived bioproduct valorization. It synthesizes seven evidence streams and proposes specification-adjusted route accounting, connecting route identity, output states, and claim-specific requirements. Selected elements were illustrated retrospectively using 17 purposively selected evidence packages. Artemisinin retention decreased from 90.0% after maceration to 37.3% after crystallization on the same initial artemisinin basis. Higher grapefruit-pectin yield accompanied changes in product properties without establishing functional equivalence. Red-grape-pomace economic preference depended on price assumptions. For microencapsulated pomegranate-peel extract powder, the highest deterministic net present value and highest probability of a positive net present value occurred in different modeled scale scenarios. Its separately scoped life cycle assessment identified freeze-drying as a hotspot without establishing comparative environmental improvement. No selected package provided verifiable observed-displacement evidence at the documented access level. The framework distinguishes supported conclusions from unresolved requirements; the cases illustrate its logic rather than validate its performance. Purposive selection, limited source access, and single-author assessment constrain interpretation. Independent and prospective evaluation is needed before reproducibility or decision benefits can be established.",
  "abstract_shown": true,
  "affiliations": [
    "Independent Researcher, Seoul 06300, Republic of Korea"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 1,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Hyo Jun Won",
      "orcid": "0009-0006-5149-6060"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/fnzr44jdd15zm.bib",
  "cited_by": 0,
  "doi": "10.3390/molecules31203689",
  "fulltext_url": null,
  "id": "fnzr44jdd15zm",
  "issns": [
    "1420-3049"
  ],
  "landing_url": "https://www.mdpi.com/1420-3049/31/20/3689",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1106|Agricultural and Biological Research"
    ]
  ],
  "openalex": "W7214129225",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-15",
  "publisher": "MDPI AG",
  "ris": "https://research.draconitic.com/paper/fnzr44jdd15zm.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:42Z",
      "native_id": "10.3390/molecules31203689",
      "source": "crossref",
      "url": "https://www.mdpi.com/1420-3049/31/20/3689"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "issn:1420-3049",
      "subfield": "general"
    }
  ],
  "title": "Laboratory-to-Industrial Translation in Plant-Derived Bioproduct Valorization: A Critical Integrative Review and Proposed Framework for Route-Level Evidence Assessment",
  "title_text": "Laboratory-to-Industrial Translation in Plant-Derived Bioproduct Valorization: A Critical Integrative Review and Proposed Framework for Route-Level Evidence Assessment",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:18:42Z",
  "url": "https://research.draconitic.com/paper/fnzr44jdd15zm",
  "venue": "Molecules",
  "versions": []
}