{
  "abstract": "Precise inner-wall modification of macrocyclic arenes remains a formidable challenge in supramolecular chemistry due to the scarcity of available synthetic strategies. Herein, we report the design and synthesis of a novel meta-carborane-based macrocyclic arene featuring a rigid triangular prismatic cavity. By finely tuning the stoichiometry of tetrabutylammonium fluoride (TBAF), we achieved the first stepwise inner-wall functionalization of this macrocyclic system via the controllable deboronation of closo-meta-carborane units, selectively affording mono-, bis-, and tris-nido-carborane-modified products in high isolated yields. This approach enables programmable modulation of the cavity electrostatic microenvironment under mild conditions with high site selectivity. In addition, a metal-free oxidative B–N coupling reaction was employed to achieve inner-wall postmodification. Notably, covalent attachment of fluorophores to the macrocyclic scaffold leads to a significant enhancement of emission intensity, which is tentatively attributed to the restriction of intramolecular motions (RIM) imposed by the macrocyclic framework. This work establishes a new paradigm for the inner-wall engineering of macrocyclic arenes and substantially broadens the application horizons of carborane-based supramolecular chemistry.",
  "abstract_shown": true,
  "affiliations": [
    "Nanjing University of Science and Technology , , ,",
    "Heze University , , ,",
    "Hebei Agricultural University , , ,",
    "Nanjing University , , ,",
    "Shanxi Applied Physics and Chemistry Research Institute , , ,",
    "The Key Laboratory of Functional Molecular Solids, Ministry of Education , ,"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Ying-Zheng Ren"
    },
    {
      "affs": [
        2
      ],
      "name": "Xiao-Jian Ren"
    },
    {
      "affs": [
        0
      ],
      "name": "Lu-Qi Guo"
    },
    {
      "affs": [
        0
      ],
      "name": "Lin-Yan Xia"
    },
    {
      "affs": [
        3
      ],
      "name": "Xin-Ran Liu"
    },
    {
      "affs": [
        0,
        4,
        5
      ],
      "name": "Peng-Fei Cui",
      "orcid": "0009-0001-8104-8617"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/fqmvxphxpenjx.bib",
  "cited_by": 0,
  "doi": "10.1021/jacsau.6c01203",
  "fulltext_url": null,
  "id": "fqmvxphxpenjx",
  "issns": [
    "2691-3704"
  ],
  "landing_url": "https://pubs.acs.org/jaaucr/article/doi/10.1021/jacsau.6c01203/5454107/meta-Carborane-Based-Macrocyclic-Arenes-Synthesis",
  "language": null,
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2741|Boron Compounds in Chemistry"
    ]
  ],
  "openalex": "W7223046765",
  "pdf_url": "https://pubs.acs.org/doi/pdf/10.1021/jacsau.6c01203",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-20",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/fqmvxphxpenjx.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:36Z",
      "native_id": "10.1021/jacsau.6c01203",
      "source": "crossref",
      "url": "https://pubs.acs.org/jaaucr/article/doi/10.1021/jacsau.6c01203/5454107/meta-Carborane-Based-Macrocyclic-Arenes-Synthesis"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2741|Boron Compounds in Chemistry",
      "subfield": "imaging"
    }
  ],
  "title": "meta -Carborane-Based Macrocyclic Arenes: Synthesis and Inner-Wall Modification",
  "title_text": "meta -Carborane-Based Macrocyclic Arenes: Synthesis and Inner-Wall Modification",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:18:36Z",
  "url": "https://research.draconitic.com/paper/fqmvxphxpenjx",
  "venue": "JACS Au",
  "versions": []
}