{
  "abstract": "Background: Klebsiella pneumoniae is a key causative agent of multidrug resistant nosocomial infections. Bacteriophages offer a promising alternative treatment, but the diversity of Klebsiella species requires the characterisation of a broad range of phages, particularly the poorly characterised jumbo phages. Materials and Methods: Phage BMCPR_005026 was isolated from sewage against Klebsiella pneumoniae. Whole genome sequencing, transmission electron microscopy and host range analysis against a diverse set of 40 clinically relevant Klebsiella strains were used to characterise the phage. Results: The virion had a myovirus morphology and genomic analysis placed it within an undefined family in Caudoviricetes where it forms a new species within the genus Alcyoneusvirus. BMCPR_005026 could form plaques on 3 of the 40 Klebsiella strains tested (7.5%) and formed halos. Conclusion: BMCPR_005026 represents a new species of phage within the genus Alcyoneusvirus with activity against 3 Klebsiella KL-types.",
  "abstract_shown": true,
  "affiliations": [
    "University of Leicester"
  ],
  "article_type": "New results",
  "arxiv": null,
  "author_total": 15,
  "authors": [
    {
      "name": "I. Lloyd-Evans"
    },
    {
      "name": "M. Ford"
    },
    {
      "name": "J. Hazzard"
    },
    {
      "name": "C. Bartis"
    },
    {
      "name": "F. Patel"
    },
    {
      "name": "N. Roemer"
    },
    {
      "name": "K. Wright"
    },
    {
      "name": "K. Porter"
    },
    {
      "name": "M. Coleman"
    },
    {
      "name": "E. Galyov"
    },
    {
      "name": "S. Megremis"
    },
    {
      "name": "M. R. Clokie"
    },
    {
      "name": "A. D. Millard"
    },
    {
      "name": "S. Michniewski"
    },
    {
      "affs": [
        0
      ],
      "name": "R. C. Wilkinson"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/fszy1gkjkstsw.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.09.30.755614",
  "fulltext_url": "https://www.biorxiv.org/content/10.64898/2026.09.30.755614v1.full",
  "id": "fszy1gkjkstsw",
  "issns": [],
  "landing_url": "https://www.biorxiv.org/content/10.64898/2026.09.30.755614v1",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "biorxiv",
      "microbiology"
    ],
    [
      "openalex",
      "2303|Bacteriophages and microbial interactions"
    ]
  ],
  "openalex": "W7215028219",
  "pdf_url": "https://www.biorxiv.org/content/10.64898/2026.09.30.755614v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-30",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/fszy1gkjkstsw.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:25:44Z",
      "native_id": "10.64898/2026.09.30.755614",
      "source": "biorxiv",
      "url": "https://www.biorxiv.org/content/10.64898/2026.09.30.755614v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "biorxiv:microbiology",
      "subfield": "microbiology"
    }
  ],
  "title": "Isolation and characterisation of Lytic Jumbo Klebsiella phage BMPCR_005026",
  "title_text": "Isolation and characterisation of Lytic Jumbo Klebsiella phage BMPCR_005026",
  "type": "preprint",
  "updated_at": "2026-10-30T12:25:44Z",
  "url": "https://research.draconitic.com/paper/fszy1gkjkstsw",
  "venue": "bioRxiv",
  "versions": []
}