{
  "abstract": "Background: Melasma is a commonly acquired hyperpigmentation disorder.\n\nObjectives: This is a retrospective, clinical study conducted to evaluate the use of 675 nm wavelength laser treatment in Indian patients affected by facial melasma.\n\nMethods: A total of 52 patients with clinically diagnosed melasma were treated with a 675 nm laser system. All participants underwent 4 treatment sessions, each performed at 27 ± 7 day intervals. Patient's pigment reduction and skin homogeneity were assessed with photographic documentation and with the use of the modified Melasma Area and Severity Index at baseline, and 3-month follow-up after the last laser treatment. In addition, patients’ satisfaction scores were evaluated.\n\nResults: Modified Melasma Area and Severity Index score significantly decreased from 3.8 ± 2.3 at baseline to 2.8 ± 1.7 after treatment. The photographic assessment was consistent with a reduction in pigmentation following treatment. Concerning patient satisfaction scores, 13% of participants reported not being satisfied, 29% were slightly satisfied, 32% were moderately satisfied, and 26% were very satisfied with the overall treatment outcome. There were no major adverse effects reported during the treatment period.\n\nConclusions: The application of the 675 nm laser was associated with short-term improvement to reduce pigmentary symptoms associated with facial melasma in both Indian men and women. However, the retrospective design, absence of a control group, and relatively short follow-up period limit the strength of these findings. Further prospective controlled studies with longer follow-up are needed to confirm efficacy and durability of results.\n\nLevel of Evidence: 4 (Therapeutic):",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "name": "Ruta Joshi"
    },
    {
      "name": "Ojas Kulkarni"
    },
    {
      "name": "Irene Fusco",
      "orcid": "0000-0001-7264-8808"
    },
    {
      "name": "Tiziano Zingoni",
      "orcid": "0009-0008-8688-7787"
    },
    {
      "name": "Dipak Kulkarni"
    },
    {
      "name": "Swapnil Shah"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/fv8hg7fcypbqc.bib",
  "cited_by": 0,
  "doi": "10.1093/asjof/ojag191",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13696835/",
  "id": "fv8hg7fcypbqc",
  "issns": [
    "2631-4797"
  ],
  "landing_url": "https://doi.org/10.1093/asjof/ojag191",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "AcademicSubjects/MED00987"
    ],
    [
      "heading",
      "Asj/1"
    ],
    [
      "heading",
      "Original Article"
    ],
    [
      "openalex",
      "2708|Dermatologic Treatments and Research"
    ]
  ],
  "openalex": "W7215116124",
  "pdf_url": "https://europepmc.org/articles/PMC13696835?pdf=render",
  "pmcid": "PMC13696835",
  "pmid": "42936100",
  "published": "2026-10-01",
  "publisher": "Oxford University Press",
  "ris": "https://research.draconitic.com/paper/fv8hg7fcypbqc.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:07Z",
      "native_id": "PMC13696835",
      "source": "pmc",
      "url": "https://doi.org/10.1093/asjof/ojag191"
    },
    {
      "first_seen": "2026-10-30T12:22:24Z",
      "native_id": "MED:42936100",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42936100"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2708|Dermatologic Treatments and Research",
      "subfield": "general"
    }
  ],
  "title": "Clinical Experience With the Use of a 675 nm Laser System With a Faster Treatment Strategy for Melasma in Indian Patients",
  "title_text": "Clinical Experience With the Use of a 675 nm Laser System With a Faster Treatment Strategy for Melasma in Indian Patients",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:34:06Z",
  "url": "https://research.draconitic.com/paper/fv8hg7fcypbqc",
  "venue": "Aesthetic Surgery Journal. Open Forum",
  "versions": []
}