{
  "abstract": "Programmable dissipative systems that mimic life’s ability to execute timed functions—such as apoptosis triggered by inherent reactivity contrasts—remain a fundamental challenge, as most synthetic designs lack the kinetic complexity to orchestrate multi-step, autonomous sequences. Here, we introduce a synthetic dissipative network in which the intrinsic oxidation kinetics of mono- and dithiols serve as an embedded reaction window to program a cascade of thiol-thioester exchange reactions. This autonomous mechanism dictates reaction timing and sequence, translating molecular-scale kinetic differences into a programmed, system-level response. By extending this principle to the material scale, we further construct fuel-driven, self-assembled vesicles that undergo a life-like cycle of formation, functional execution (as catalytic microreactors), and dissipation. This work establishes intrinsic kinetic hierarchies as a general design paradigm for programming temporal order in non-equilibrium systems, inspiring the development of time-evolving functional materials.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "name": "Yingjie Huang",
      "orcid": "0000-0002-0145-4173"
    },
    {
      "name": "Yulu Wang"
    },
    {
      "name": "Hui Zhao"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/fx28cqtpejv3q.bib",
  "cited_by": 0,
  "doi": "10.26434/chemrxiv.15010879/v1",
  "fulltext_url": null,
  "id": "fx28cqtpejv3q",
  "issns": [],
  "landing_url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15010879/v1",
  "language": null,
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1605|Supramolecular Chemistry and Complexes"
    ]
  ],
  "openalex": "W7223182345",
  "pdf_url": "https://chemrxiv.org/doi/pdf/10.26434/chemrxiv.15010879/v1",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-22",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/fx28cqtpejv3q.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:26Z",
      "native_id": "10.26434/chemrxiv.15010879",
      "source": "chemrxiv",
      "url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15010879/v1"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1605|Supramolecular Chemistry and Complexes",
      "subfield": "organic"
    }
  ],
  "title": "Programming of Dissipative Networks and Transient Vesicles Using Intrinsic Kinetic Discrimination of Thiol Oxidation",
  "title_text": "Programming of Dissipative Networks and Transient Vesicles Using Intrinsic Kinetic Discrimination of Thiol Oxidation",
  "type": "preprint",
  "updated_at": "2026-10-30T12:17:26Z",
  "url": "https://research.draconitic.com/paper/fx28cqtpejv3q",
  "venue": "ChemRxiv",
  "versions": []
}