{
  "abstract": "Introduction: Maintaining an adequate blood component inventory requires balancing donor recruitment with transfusion demand. In the Brazilian Amazon, vast distances, reliance on river transportation, and seasonal hydrological variations pose additional challenges to blood component inventory management. Objectives: To evaluate operational indicators related to blood supply, demand, losses, and transfusion request compliance at the Manacapuru Blood Center, Amazonas, Brazil. Materials and methods: This retrospective observational study used secondary data from the Manacapuru Blood Center collected between January 2023 and September 2025. The study was approved by the institutional Research Ethics Committee. Donor recruitment, transfusions performed, collection-to-transfusion ratio (CTR), transfusion request compliance, and packed red blood cell losses were evaluated. Descriptive statistics, chi-square tests for trend and group comparisons, Fisher's exact test (α = 0.05), and seasonal analyses comparing flood and dry seasons were performed. Results: A total of 1,333 blood donations and 936 transfusions were analyzed. Although blood supply remained sufficient to meet transfusion demand, the CTR increased progressively from 1.24 in 2023 to 1.53 in 2024 and 1.56 in 2025, accompanied by a significant increase in losses relative to collections (14.3%, 26.2%, and 27.4%, respectively; p < 0.001). Expiration accounted for more than 92% of discarded units throughout the study period, with no significant variation in discard causes between years (Fisher's exact test, p = 0.080), suggesting a mismatch between blood supply and transfusion demand. Transfusion requests showed high compliance with institutional protocols, with only rare non-conformities in emergency situations. Donor recruitment was higher during the dry season than during the flood season (41.5 vs. 36.4 donors/month). Discussion: The operational indicators demonstrated adequate transfusion coverage but revealed a progressive mismatch between blood supply and demand, reflected by the simultaneous increase in the CTR and expiration-related losses. The observed seasonal variation may reflect the logistical challenges characteristic of the Brazilian Amazon, whereas the high compliance of transfusion requests indicates appropriate blood utilization consistent with PBM principles. Conclusion: The Manacapuru Blood Center provides adequate transfusion coverage but presents opportunities to improve inventory management and reduce expiration-related losses. Continuous monitoring of operational indicators, combined with Patient Blood Management strategies tailored to the Amazonian context, may improve inventory planning, better align blood supply with transfusion demand, and optimize blood component utilization.",
  "abstract_shown": true,
  "affiliations": [
    "Afya Faculdade de Ciências Médicas de Manacapuru (AFYA), Manacapuru, Brazil"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Juliane Kátia Moreira dos Santos CERINO"
    },
    {
      "affs": [
        0
      ],
      "name": "Emely Karen Dos Santos GANOZA"
    },
    {
      "affs": [
        0
      ],
      "name": "Janderson Barbosa de SOUZA"
    },
    {
      "affs": [
        0
      ],
      "name": "Paulo Mendes GUERREIRO"
    },
    {
      "affs": [
        0
      ],
      "name": "Nadielle Castro PEREIRA"
    },
    {
      "affs": [
        0
      ],
      "name": "Erick Frota Gomes FIGUEIREDO"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/fx9zvpnb5nznc.bib",
  "cited_by": 0,
  "doi": "10.1016/j.htct.2026.107207",
  "fulltext_url": "http://www.sciencedirect.com/science/article/pii/S2531137926009545",
  "id": "fx9zvpnb5nznc",
  "issns": [
    "2531-1379",
    "2531-1387"
  ],
  "landing_url": "https://doi.org/10.1016/j.htct.2026.107207",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "RC633-647.5"
    ],
    [
      "openalex",
      "1405|Blood donation and transfusion practices"
    ]
  ],
  "openalex": "W7223133846",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-23",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/fx9zvpnb5nznc.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:43:19Z",
      "native_id": "4ff3283387a1470e9f0a6762296bbfcd",
      "source": "doaj",
      "url": "https://doi.org/10.1016/j.htct.2026.107207"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "lcc:RC633-647.5",
      "subfield": "endocrinology-metabolism"
    }
  ],
  "title": "OPERATIONAL INDICATORS OF BLOOD COMPONENT INVENTORY MANAGEMENT AT THE MANACAPURU BLOOD CENTER, AMAZONAS, BRAZIL",
  "title_text": "OPERATIONAL INDICATORS OF BLOOD COMPONENT INVENTORY MANAGEMENT AT THE MANACAPURU BLOOD CENTER, AMAZONAS, BRAZIL",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:43:19Z",
  "url": "https://research.draconitic.com/paper/fx9zvpnb5nznc",
  "venue": "Hematology, Transfusion and Cell Therapy",
  "versions": []
}