{
  "abstract": "Objectives\n\nDilated cardiomyopathy (DCM) with severe left ventricular (LV) dysfunction in infants and young children is a life-threatening condition and carries a high risk of mechanical circulatory support and heart transplantation (HTx). Pulmonary artery banding (PAB) has been proposed as a recovery strategy, but data on medium- and long-term outcomes remain limited.Methods\n\nThis retrospective, single-center observational study included infants and young children who underwent surgical PAB between 2006 and 2024. Inclusion criteria were ROSS functional class (FC) III/IV, spherical left ventricular-dilated cardiomyopathy (LV-DCM) with left ventricular ejection fraction (LVEF) <35%, and left ventricular end-diastolic diameter (LVEDD) z-score >+4 with preserved right ventricular function. Primary endpoints were overall survival and transplant-free recovery, defined as sustained normalization of LV systolic function with reverse remodeling.Results\n\nFifty patients (27 female) met the inclusion criteria and underwent PAB at a median age of 188 days, 70% were in ROSS FC IV, and 42% were listed as urgent for HTx. DCM etiology was idiopathic in 42%, genetic in 22%, and myocarditis-associated in 36%. There was no procedural mortality. Overall survival was 90% and 72% achieved transplant-free functional recovery. Following PAB, magnetic resonance imaging-derived LVEF improved from 19% ± 7% to 56% ± 11%, and LVEDD z-scores decreased from +6.3 to +1 (P < .001). In 33 patients, recovery was sustained over a median follow-up of 7 years, including 15 patients with stable LV function for over 10 years.Conclusions\n\nIn infants and young children with severe LV-DCM, PAB is associated with high long-term survival, sustained transplant-free recovery, and durable reverse cardiac remodeling.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Pediatric Cardiology, Intensive Care Medicine and Congenital Heart Disease, Pediatric Heart Center, Justus-Liebig-University, Giessen, Germany.",
    "Department of Pediatric Cardiology, Goethe University, University Hospital Frankfurt, Frankfurt, Germany.",
    "Cardiopathology, Institute for Pathology and Neuropathology, University Hospital Tübingen, Tübingen, Germany.",
    "Department of Pediatric Cardiac Anesthesiology, Pediatric Heart Center, Justus-Liebig-University, Giessen, Germany.",
    "Department of Pediatric Cardiology, German Heart Center Munich, Technical University of Munich, Munich, Germany.",
    "Department of General and Interventional Cardiology/Angiology, Ruhr University Bochum, Heart- and Diabetescenter NRW, Bad Oeynhausen, Germany.",
    "Department of Pediatric Cardiac Surgery and Congenital Heart Disease, Pediatric Heart Center, Justus-Liebig-University, Giessen, Germany."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 12,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Thushiha Logeswaran"
    },
    {
      "affs": [
        0
      ],
      "name": "Blanka Steinbrenner"
    },
    {
      "affs": [
        1
      ],
      "name": "Dietmar Schranz"
    },
    {
      "affs": [
        0
      ],
      "name": "Sabine Recla"
    },
    {
      "affs": [
        2
      ],
      "name": "Karin Klingel"
    },
    {
      "affs": [
        3
      ],
      "name": "Matthias Müller"
    },
    {
      "affs": [
        0
      ],
      "name": "Kerstin Gummel"
    },
    {
      "affs": [
        0
      ],
      "name": "Lucie Rüblinger"
    },
    {
      "affs": [
        4
      ],
      "name": "Bettina Reich"
    },
    {
      "affs": [
        5
      ],
      "name": "Martin Farr"
    },
    {
      "affs": [
        0
      ],
      "name": "Christian Jux"
    },
    {
      "affs": [
        6
      ],
      "name": "Hakan Akintürk"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/fybb5mwjpqgwc.bib",
  "cited_by": 0,
  "doi": "10.1016/j.xjon.2026.102088",
  "fulltext_url": "https://europepmc.org/articles/PMC13711275",
  "id": "fybb5mwjpqgwc",
  "issns": [
    "2666-2736"
  ],
  "landing_url": "https://europepmc.org/article/MED/42948132",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Congenital: Pulmonary Artery"
    ],
    [
      "openalex",
      "2713|Congenital Heart Disease Studies"
    ]
  ],
  "openalex": "W7204557546",
  "pdf_url": "https://europepmc.org/articles/PMC13711275?pdf=render",
  "pmcid": "PMC13711275",
  "pmid": "42948132",
  "published": "2026-08-28",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/fybb5mwjpqgwc.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T00:20:35Z",
      "native_id": "MED:42948132",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42948132"
    },
    {
      "first_seen": "2026-10-31T12:22:05Z",
      "native_id": "PMC13711275",
      "source": "pmc",
      "url": "https://doi.org/10.1016/j.xjon.2026.102088"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2713|Congenital Heart Disease Studies",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Two decades of targeted pulmonary artery banding in pediatric dilated cardiomyopathy.",
  "title_text": "Two decades of targeted pulmonary artery banding in pediatric dilated cardiomyopathy.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-31T12:22:05Z",
  "url": "https://research.draconitic.com/paper/fybb5mwjpqgwc",
  "venue": "JTCVS open",
  "versions": []
}