{
  "abstract": "A simple, one-pot method for the synthesis of seven novel dihydrothiazole-hydrazone compounds is presented, employing a condensation-cyclization protocol, with the products characterized by FTIR, 1H NMR, 13C NMR, and ESI-MS. Thiazoles and hydrazones are distinguished by versatile chelating properties and fluorescent conjugated scaffolds, and their combination can be considered a promising route to obtaining tunable fluorophores. According to the UV-Vis absorption and fluorescence data, all seven compounds demonstrated absorption maxima at 412–420 nm and emitted a yellow-green light at 554–575 nm. The substituent present at the C-4 position of the dihydrothiazole ring governed the emission wavelength and intensity. Electron-donating groups increased emission intensity and shifted the emission to longer wavelengths, whereas electron-withdrawing groups quenched fluorescence, likely via a photoinduced electron transfer (PET) deactivation mechanism. The Stokes shifts (142–155 nm) also followed the same substituent-dependent pattern. Moderate fluorescence quantum yields (1.64–5.54%) were observed for the thiazoles, indicating that the presence of different functional groups influenced the efficiency of excited-state relaxation. The way substitution influences absorption and emission behavior establishes the dihydrothiazole-hydrazone core as a versatile unit that can be tuned to serve as a fluorophore for sensing, biological, and optoelectronic applications.\n\nGraphical Abstract:\n\nSupplementary Information: The online version contains supplementary material available at https://doi.org/10.1007/s10895-026-04955-6.",
  "abstract_shown": true,
  "affiliations": [
    "Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, India"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Charan D. C."
    },
    {
      "affs": [
        0
      ],
      "name": "Yogeesh M."
    },
    {
      "affs": [
        0
      ],
      "name": "Nitinkumar S. Shetty",
      "orcid": "0000-0002-7590-1693"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/fz5knxf2en57w.bib",
  "cited_by": 0,
  "doi": "10.1007/s10895-026-04955-6",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13722728/",
  "id": "fz5knxf2en57w",
  "issns": [
    "1053-0509",
    "1573-4994"
  ],
  "landing_url": "https://doi.org/10.1007/s10895-026-04955-6",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Research"
    ],
    [
      "openalex",
      "2505|Luminescence and Fluorescent Materials"
    ]
  ],
  "openalex": "W7214668438",
  "pdf_url": "https://link.springer.com/content/pdf/10.1007/s10895-026-04955-6.pdf",
  "pmcid": "PMC13722728",
  "pmid": "42806234",
  "published": "2026-09-29",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/fz5knxf2en57w.ris",
  "sources": [
    {
      "first_seen": "2026-11-04T12:21:29Z",
      "native_id": "PMC13722728",
      "source": "pmc",
      "url": "https://doi.org/10.1007/s10895-026-04955-6"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:2505|Luminescence and Fluorescent Materials",
      "subfield": "materials-polymers"
    }
  ],
  "title": "One-Pot Synthesis of Dihydrothiazole-Hydrazone Hybrids and Evaluation of Their Absorption and Emission Properties",
  "title_text": "One-Pot Synthesis of Dihydrothiazole-Hydrazone Hybrids and Evaluation of Their Absorption and Emission Properties",
  "type": "peer-reviewed",
  "updated_at": "2026-11-04T12:21:29Z",
  "url": "https://research.draconitic.com/paper/fz5knxf2en57w",
  "venue": "Journal of Fluorescence",
  "versions": []
}