{
  "abstract": "Macrophage involvement in the human response to ozone remains poorly defined. In this human crossover exposure study, we characterized ozone-induced changes in airway macrophage populations at 24, 48, and 72 h post-exposure. Ozone exposure caused immediate declines in pulmonary function, which improved 24-72 h later; recovery was associated with increases in airway monocyte-derived macrophage-to-neutrophil and monocyte-derived macrophage-to-monocyte ratios. These findings highlight coordinated, time-related macrophage dynamics that may contribute to recovery from ozone-induced lung injury.",
  "abstract_shown": true,
  "affiliations": [
    "Division of Pulmonary and Critical Care Medicine, Department of Medicine, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, New Jersey, USA",
    "Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, New Jersey, USA",
    "Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey, USA",
    "Department of Environmental and Occupational Health and Justice, Rutgers School of Public Health, Piscataway, New Jersey, USA"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 12,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Jared Radbel"
    },
    {
      "affs": [
        2
      ],
      "name": "Emily R. Stevenson"
    },
    {
      "affs": [
        2
      ],
      "name": "Raymond C. Rancourt"
    },
    {
      "affs": [
        1
      ],
      "name": "Kathleen G. Black"
    },
    {
      "affs": [
        1
      ],
      "name": "Adriana De Resende"
    },
    {
      "affs": [
        0
      ],
      "name": "Derek Ge"
    },
    {
      "affs": [
        0
      ],
      "name": "Aesha Jobanputra"
    },
    {
      "affs": [
        2
      ],
      "name": "Jessica Cervelli"
    },
    {
      "affs": [
        3,
        1
      ],
      "name": "Jeffrey D. Laskin"
    },
    {
      "affs": [
        3,
        1
      ],
      "name": "Howard M. Kipen"
    },
    {
      "affs": [
        2,
        1
      ],
      "name": "Andrew J. Gow"
    },
    {
      "affs": [
        2,
        1
      ],
      "name": "Debra L. Laskin"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/fzw9ee5ygvd3r.bib",
  "cited_by": 0,
  "doi": "10.1152/ajplung.00120.2026",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13718308/",
  "id": "fzw9ee5ygvd3r",
  "issns": [
    "1040-0605",
    "1522-1504"
  ],
  "landing_url": "https://doi.org/10.1152/ajplung.00120.2026",
  "language": "en",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Article"
    ],
    [
      "openalex",
      "2307|Air Quality and Health Impacts"
    ]
  ],
  "openalex": "W7214377140",
  "pdf_url": null,
  "pmcid": "PMC13718308",
  "pmid": "42789969",
  "published": "2026-09-21",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/fzw9ee5ygvd3r.ris",
  "sources": [
    {
      "first_seen": "2026-11-02T12:22:21Z",
      "native_id": "PMC13718308",
      "source": "pmc",
      "url": "https://doi.org/10.1152/ajplung.00120.2026"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2307|Air Quality and Health Impacts",
      "subfield": "pharmacology-toxicology"
    }
  ],
  "title": "Dynamics of Airway Macrophage Responses and Lung Function Changes after Ozone Exposure in Humans",
  "title_text": "Dynamics of Airway Macrophage Responses and Lung Function Changes after Ozone Exposure in Humans",
  "type": "peer-reviewed",
  "updated_at": "2026-11-02T12:22:21Z",
  "url": "https://research.draconitic.com/paper/fzw9ee5ygvd3r",
  "venue": "American journal of physiology. Lung cellular and molecular physiology",
  "versions": []
}