Cell biology
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- A Thermodynamic Framework Linking Black Box Growth models with Genome Scale Metabolite models
- Glutamine-regulated VCP acetylation creates a proteostasis vulnerability in RB1-deficient tumor
- AMPK reinforces mitochondrial metabolism and suppresses pathological remodeling in Complex V-deficient cardiomyocytes
- Aberrant PCM1 accumulation in Trisomy 21 mislocalizes E3 ligases, delaying primary ciliogenesis
- High-resolution CRISPR/Cas9 screens identify PAK2 as a suppressor of macrophage proliferation
- PER2- and state-dependent transcriptional programs gate neural stem cell proliferation with niche-specific circadian autonomy
- H3-K27M mutation alters the dynamics of human hematopoietic stem cells and delays erythroid differentiation
- 3' Plasma Membrane Phosphoinositides Sustain ROS Production at Persistent Non-canonical Phagocytic Cups that Promote Macrophage Control of Aspergillus fumigatus Hyphae
- PBF/PTTG1IP coordinates focal adhesion formation, polarity and cell motility
- Emerin loss of function inhibits MyoD-driven differentiation of human iPSCs into skeletal myotubes
- SIM2s coordinates programmed mitophagy with respiratory chain supercomplex remodeling during mammary epithelial differentiation
- Paneth cell-derived Notch ligands DLL1 and DLL4 are crucial for intestinal crypt base stem cells.
- QUANTITATIVE PROTEOMIC REVEALS HEME OXYGENASE-1 LOCALIZATION TO CELL-SURFACE LIPID RAFTS AND ITS ASSOCIATION WITH FERROPORTIN IN IRON-LOADED MACROPHAGES
- LNA043 and ANGPTL3 Interactions with Integrin α5β1 and Fibronectin Drive Distinct Stromal and Immune Responses
- Optical microelectrode arrays for differential readout of electrical and mechanical signals in cardiac cells
- Speed and stability of segregated waves in a pressure-based model of heterogeneous cell populations
- Distinct regulation of collagen biosynthesis by hypoxia and vitamin C uncovers an essential role for CXCL12-CXCR4 signaling
- Chemotherapy and neuroprotection: one carbazole compound, two functions
- Calcium trafficking in the mussel Mytilus galloprovincialis suggests conserved biomineralization pathways
- Citron Kinase, a mitotic kinase with increasing significance in cancer
- Evolutionary diversification of the nuclear pore complex in Entamoeba histolytica reveals conserved and lineage-specific nucleoporins
- Parthenolide boosts megakaryocyte maturation and restores platelet responses in Wiskott Aldrich syndrome
- Mitochondrial dysfunction and impaired osteogenic capacity define stress-induced osteoblast senescence
- An INSR-BECN1-KIAA0825 complex prevents hepatocytic insulin receptor secretion via extracellular vesicles against monogenic diabetes
- Chemically induced USP21-KLHL12 association recruits USP21 to COPII assembly