Immunology
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- Severe pneumonia-associated lung injury: gut-lung-immune-metabolic connections in the critically ill host environment-microecology, barrier function, and mechanical ventilation
- Interferon regulatory factor 1: a key transcriptional node orchestrating macrophage polarization: mechanisms and therapeutic potential
- Mechanistic advances in neutrophil extracellular traps promoting tumor invasion via the PAR2 signaling axis
- MELD-S prognostic model: development and external validation for 90-day mortality prediction in acute-on-chronic liver failure
- Large-scale plasma proteomics identifies proteins and pathways associated with incident interstitial lung disease
- Age-stratified analysis reveals heterogeneity in factors associated with gastrointestinal bleeding in IgA vasculitis: a retrospective study in a large volume center
- Brentuximab vedotin plus CHP-like versus CHOEP regimen for the first-line treatment of PTCL patients: a multi-center propensity-matched retrospective study
- Development of an IL-6- and Th1/Treg-based nomogram for identifying low bone mass in patients with rheumatoid arthritis
- Targeting P2Y12 limits TH17 accumulation in the CNS and reduces EAE progression
- Brucella melitensis bacteraemia with lymphoma-like generalised lymphadenopathy and probable secondary haemophagocytic lymphohistiocytosis under biopsy constraints: a case report
- Integrating multi-omics and machine learning to reveal IL1R2-driven macrophage-fibroblast spatial interactions in polycyclic aromatic hydrocarbon-induced pulmonary fibrosis
- Editorial: The expanding spectrum of hemophagocytic lymphohistiocytosis: pathogenic mechanisms and therapeutic implications
- Weissella koreensis regulates mitochondrial protective genes and innate immune genes to enhance anti-bacterial immunity
- Case Report: Dupilumab-associated psoriasiform eruption followed by depigmentation in a patient with prurigo nodularis and Vogt-Koyanagi-Harada disease
- Cytokine-Mediated Plasticity in the Molecular Requirements for Peptide-Loading Complex Formation and Antigen Presentation
- Tumor-Centric Immune Crosstalk in Colorectal and Gastric Cancer: Molecular Mechanisms Linking Tumor Cells to Macrophages and CD8+ T Lymphocytes
- The critical role of the endogenous immune compartment after CAR T cell therapy in recurrent GBM
- IRAK4 autophosphorylation functions as a molecular switch to regulate death domain assembly and Myddosome maturation
- Tumor-intrinsic PTPN12 suppresses anti-tumor immunity in colorectal cancer by restraining a dual epigenetic and cytoskeletal dsRNA sensing program
- Immunostimulatory effects of polysaccharides from Coix lacryma-jobi var. mayuen seed water-soluble extracts on immune cells via the TLR2/4-MAPK/NF-κB signaling pathway
- Analysis of the impact of naturally-acquired immunity on Shigella vaccine performance to inform clinical trials: A simulation-based modeling study
- Diverse infection models demonstrate robust resistance of Mycobacterium tuberculosis to innate immunity
- Multiscale modeling reveals non-linear dynamics of AKT-mediated NO-ROS crosstalk in shear stress-induced endothelial phenotype
- Association of admission aggregate index of systemic inflammation with lower-extremity deep vein thrombosis after severe trauma
- Multi-cohort transcriptomics and donor-aware single-cell analyses prioritize S100A8 within an emergency-myeloid, HLA-DR-low state in sepsis