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Peer-reviewedCC BY-NC-NDInternal Medicine

Giant Leiomyoma Causing Recurrent Fever of Unknown Origin

Abstract

A 45-year-old woman presented with a recurrent fever of unknown origin (FUO) for six years.She had a persistent lowgrade fever with intermittent episodes of high-grade fever lasting a few days approximately once a month, as well as progressive abdominal distension without abdominal pain.Laboratory tests, including those for inflammatory and tumor markers, were unremarkable.A physical examination revealed the presence of a pelvic mass.Magnetic resonance imaging revealed a 17-cm uterine mass with extensive cystic and hydropic degeneration (Picture A, B).Total hysterectomy was performed to relieve the symptomatic mass effect and exclude malignancy (Picture C, D).A histopathological examination

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BibTeX
@article{horino2026giant,
  title = {{Giant Leiomyoma Causing Recurrent Fever of Unknown Origin}},
  author = {Taro Horino},
  journal = {Internal Medicine},
  year = {2026},
  month = sep,
  doi = {10.2169/internalmedicine.7972-26},
  url = {https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7972-26/_article},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Giant Leiomyoma Causing Recurrent Fever of Unknown Origin
AU  - Taro Horino
PY  - 2026
DA  - 2026/09/01
JO  - Internal Medicine
DO  - 10.2169/internalmedicine.7972-26
UR  - https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7972-26/_article
AB  - A 45-year-old woman presented with a recurrent fever of unknown origin (FUO) for six years.She had a persistent lowgrade fever with intermittent episodes of high-grade fever lasting a few days approximately once a month, as well as progressive abdominal distension without abdominal pain.Laboratory tests, including those for inflammatory and tumor markers, were unremarkable.A physical examination revealed the presence of a pelvic mass.Magnetic resonance imaging revealed a 17-cm uterine mass with extensive cystic and hydropic degeneration (Picture A, B).Total hysterectomy was performed to relieve the symptomatic mass effect and exclude malignancy (Picture C, D).A histopathological examination
SN  - 1349-7235
SN  - 0918-2918
ER  -