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Peer-reviewedCC BYCase reports in surgery

Giant Duodenal Perforation Secondary to Malaria in a 5-Year-Old Girl: Case Report and Review.

  • Ashenafi Shegaw1
  • Mahiderekal Mengistu Berkit2
  • Milki Tufa3
  • Alo Edin4
4 affiliations
  1. 1Department of Surgery Institute of Health Bule Hora University Teaching Hospital Bule Hora University Bule Hora Ethiopia bhu.edu.et.
  2. 2School of Medicine Institute of Health Bule Hora University Bule Hora Ethiopia bhu.edu.et.
  3. 3Department of Pediatrics and Child Health Institute of Health Bule Hora University Teaching Hospital Bule Hora University Bule Hora Ethiopia bhu.edu.et.
  4. 4Department of Epidemiology School of Public Health Institute of Health Bule Hora University Bule Hora Ethiopia bhu.edu.et.
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Abstract

Background

Peptic ulcer disease (PUD) is rare in children, with complications like perforation being especially uncommon. Malaria, a major health burden in endemic regions, is associated with severe complications, but giant duodenal perforation as a direct consequence is remarkably rare. This report presents a 5-year-old girl with a giant duodenal perforation secondary to malaria, highlighting the need for prompt diagnosis and intervention.Case presentation

A 5-year-old girl from a malaria-endemic area presented with fever, vomiting, and diarrhea. Diagnosed with severe malaria, she developed acute abdominal pain and signs of peritonitis. Imaging confirmed duodenal perforation, which was surgically repaired. Postoperative recovery was successful, and Helicobacter pylori infection was ruled out.Conclusion

Giant duodenal perforation can occur as a rare complication of severe malaria in children without typical peptic ulcer risk factors. Early recognition and timely surgical and antimalarial treatment are critical to improving outcomes in malaria-endemic settings.

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Cite

BibTeXRIS
BibTeX
@article{shegaw2026giant,
  title = {{Giant Duodenal Perforation Secondary to Malaria in a 5-Year-Old Girl: Case Report and Review.}},
  author = {Ashenafi Shegaw and Mahiderekal Mengistu Berkit and Milki Tufa and Alo Edin},
  journal = {Case reports in surgery},
  year = {2026},
  month = oct,
  doi = {10.1155/cris/5569916},
  url = {https://europepmc.org/article/MED/42910180},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Giant Duodenal Perforation Secondary to Malaria in a 5-Year-Old Girl: Case Report and Review.
AU  - Ashenafi Shegaw
AU  - Mahiderekal Mengistu Berkit
AU  - Milki Tufa
AU  - Alo Edin
PY  - 2026
DA  - 2026/10/21
JO  - Case reports in surgery
DO  - 10.1155/cris/5569916
UR  - https://europepmc.org/article/MED/42910180
AB  - Background  Peptic ulcer disease (PUD) is rare in children, with complications like perforation being especially uncommon. Malaria, a major health burden in endemic regions, is associated with severe complications, but giant duodenal perforation as a direct consequence is remarkably rare. This report presents a 5-year-old girl with a giant duodenal perforation secondary to malaria, highlighting the need for prompt diagnosis and intervention.Case presentation  A 5-year-old girl from a malaria-endemic area presented with fever, vomiting, and diarrhea. Diagnosed with severe malaria, she developed acute abdominal pain and signs of peritonitis. Imaging confirmed duodenal perforation, which was surgically repaired. Postoperative recovery was successful, and Helicobacter pylori infection was ruled out.Conclusion  Giant duodenal perforation can occur as a rare complication of severe malaria in children without typical peptic ulcer risk factors. Early recognition and timely surgical and antimalarial treatment are critical to improving outcomes in malaria-endemic settings.
SN  - 2090-6900
SN  - 2090-6919
ER  -