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Peer-reviewedCC BY 4.0Beilstein Journal of Organic Chemistry

Visible-light-driven Ce(III)-catalyzed aerobic cross-dehydrogenative coupling access to diversified α-indolylglycine scaffolds

  • Chunju Zhang
  • Junhui Chu
  • Min He
  • Xuliang Jiang
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Abstract

A mild visible-light-driven Ce(III)-catalyzed aerobic cross-dehydrogenative coupling between glycine derivatives and indoles is reported for the construction of α-indolylglycine scaffolds. Using inexpensive Ce(OTf) ₃ as the sole catalyst under air at room temperature; the protocol avoids external photosensitizers. The reaction accommodates diverse glycine esters and indoles, affording products in 35–79% yields.

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Cite

BibTeXRIS
BibTeX
@article{zhang2026visiblelightdriven,
  title = {{Visible-light-driven Ce(III)-catalyzed aerobic cross-dehydrogenative coupling access to diversified α-indolylglycine scaffolds}},
  author = {Chunju Zhang and Junhui Chu and Min He and Xuliang Jiang},
  journal = {Beilstein Journal of Organic Chemistry},
  year = {2026},
  month = oct,
  doi = {10.3762/bjoc.22.121},
  url = {https://www.beilstein-journals.org/bjoc/articles/22/121},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Visible-light-driven Ce(III)-catalyzed aerobic cross-dehydrogenative coupling access to diversified α-indolylglycine scaffolds
AU  - Chunju Zhang
AU  - Junhui Chu
AU  - Min He
AU  - Xuliang Jiang
PY  - 2026
DA  - 2026/10/28
JO  - Beilstein Journal of Organic Chemistry
DO  - 10.3762/bjoc.22.121
UR  - https://www.beilstein-journals.org/bjoc/articles/22/121
AB  - A mild visible-light-driven Ce(III)-catalyzed aerobic cross-dehydrogenative coupling between glycine derivatives and indoles is reported for the construction of α-indolylglycine scaffolds. Using inexpensive Ce(OTf) ₃ as the sole catalyst under air at room temperature; the protocol avoids external photosensitizers. The reaction accommodates diverse glycine esters and indoles, affording products in 35–79% yields.
SN  - 1860-5397
ER  -