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Peer-reviewedCC BY-NC-NDClinical case reports

Villoglandular Adenocarcinoma of the Cervix With Ovarian Metastasis Mimicking a Borderline Ovarian Tumor: A Rare Case Report.

  • Ni Ma1
  • Xiang Xu1
  • Zhengpeng Zhu2
  • Tianfang Xin2
  • Yaxiong Huang1
  1. 1Department of Obstetrics and Gynecology Sinopharm Dongfeng General Hospital, Hubei University of Medicine Shiyan Hubei China.
  2. 2Department of Pathology Sinopharm Dongfeng General Hospital, Hubei University of Medicine Shiyan Hubei China.
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Abstract

This case reports rare cervical villoglandular adenocarcinoma metastasizing to the ovary with a deceptive borderline-like morphology. Diagnosis relied on matching immunohistochemistry and HPV16 DNA detection in both sites. The patient underwent surgery and chemoradiotherapy, remaining recurrence-free. This highlights the critical need for multimodal testing to distinguish such metastases from primary ovarian tumors.

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Cite

BibTeXRIS
BibTeX
@article{ma2026villoglandular,
  title = {{Villoglandular Adenocarcinoma of the Cervix With Ovarian Metastasis Mimicking a Borderline Ovarian Tumor: A Rare Case Report.}},
  author = {Ni Ma and Xiang Xu and Zhengpeng Zhu and Tianfang Xin and Yaxiong Huang},
  journal = {Clinical case reports},
  year = {2026},
  month = oct,
  doi = {10.1002/ccr3.73677},
  url = {https://europepmc.org/article/MED/42926921},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Villoglandular Adenocarcinoma of the Cervix With Ovarian Metastasis Mimicking a Borderline Ovarian Tumor: A Rare Case Report.
AU  - Ni Ma
AU  - Xiang Xu
AU  - Zhengpeng Zhu
AU  - Tianfang Xin
AU  - Yaxiong Huang
PY  - 2026
DA  - 2026/10/24
JO  - Clinical case reports
DO  - 10.1002/ccr3.73677
UR  - https://europepmc.org/article/MED/42926921
AB  - This case reports rare cervical villoglandular adenocarcinoma metastasizing to the ovary with a deceptive borderline-like morphology. Diagnosis relied on matching immunohistochemistry and HPV16 DNA detection in both sites. The patient underwent surgery and chemoradiotherapy, remaining recurrence-free. This highlights the critical need for multimodal testing to distinguish such metastases from primary ovarian tumors.
SN  - 2050-0904
ER  -