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Peer-reviewedCC BY 4.0Scientific Reports

Cost estimate for the procurement and preparation of donated corneas for transplantation in an eye bank

2 more authors

Abstract

Corneal diseases are among the leading causes of blindness, and transplantation may be the only treatment option. Studies providing a comprehensive economic analysis of the corneal tissue processing chain, from procurement to release for transplantation by eye banks, are scarce. This study aimed to estimate the cost of preparing donated corneal tissue for transplantation at an Eye Bank. We performed a cost analysis using the Time-Driven Activity-Based Costing (TDABC) method based on data from the stages of corneal tissue preparation. The study population consisted of data from corneal donors collected in 2023. The median cost per donor was estimated at USD 454.65. Supplies (43%), human resources (32%), and operational costs (23%) were the costliest components. Multiple regression analysis identified predictors influencing costs. This study highlighted critical stages in the process and resource consumption. Investing in domestic pharmaceutical production, improving interinstitutional communication, training healthcare professionals, and providing logistical support may reduce costs and contribute to the management and sustainability of Eye Banks.

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BibTeX
@article{maidana2026cost,
  title = {{Cost estimate for the procurement and preparation of donated corneas for transplantation in an eye bank}},
  author = {Gustavo Moura Maidana and Marcos Antonio Ferreira Júnior and Oleci Pereira Frota and Isabelle Campos de Azevedo and Matilde Delmina da Silva Martins and Viviane Euzébia Pereira Santos and Felipe Machado Mota and Bethânia Karoline Alvaro Menezes and Aline Moraes da Silva and Maria Luiza Berti de Oliveira and Karina Angélica Alvarenga Ribeiro and Júlia Takamura da Silva and Gabriel Aparecido de Oliveira Ferreira and Gustavo Yuzo Oshiro Shinohara},
  journal = {Scientific Reports},
  year = {2026},
  month = oct,
  doi = {10.1038/s41598-026-73900-1},
  url = {https://www.nature.com/articles/s41598-026-73900-1},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Cost estimate for the procurement and preparation of donated corneas for transplantation in an eye bank
AU  - Gustavo Moura Maidana
AU  - Marcos Antonio Ferreira Júnior
AU  - Oleci Pereira Frota
AU  - Isabelle Campos de Azevedo
AU  - Matilde Delmina da Silva Martins
AU  - Viviane Euzébia Pereira Santos
AU  - Felipe Machado Mota
AU  - Bethânia Karoline Alvaro Menezes
AU  - Aline Moraes da Silva
AU  - Maria Luiza Berti de Oliveira
AU  - Karina Angélica Alvarenga Ribeiro
AU  - Júlia Takamura da Silva
AU  - Gabriel Aparecido de Oliveira Ferreira
AU  - Gustavo Yuzo Oshiro Shinohara
PY  - 2026
DA  - 2026/10/23
JO  - Scientific Reports
DO  - 10.1038/s41598-026-73900-1
UR  - https://www.nature.com/articles/s41598-026-73900-1
AB  - Corneal diseases are among the leading causes of blindness, and transplantation may be the only treatment option. Studies providing a comprehensive economic analysis of the corneal tissue processing chain, from procurement to release for transplantation by eye banks, are scarce. This study aimed to estimate the cost of preparing donated corneal tissue for transplantation at an Eye Bank. We performed a cost analysis using the Time-Driven Activity-Based Costing (TDABC) method based on data from the stages of corneal tissue preparation. The study population consisted of data from corneal donors collected in 2023. The median cost per donor was estimated at USD 454.65. Supplies (43%), human resources (32%), and operational costs (23%) were the costliest components. Multiple regression analysis identified predictors influencing costs. This study highlighted critical stages in the process and resource consumption. Investing in domestic pharmaceutical production, improving interinstitutional communication, training healthcare professionals, and providing logistical support may reduce costs and contribute to the management and sustainability of Eye Banks.
SN  - 2045-2322
ER  -