Cosmetic parameters associated with SRS-22r improvement postoperatively in patients with adolescent idiopathic scoliosis: a 2-year follow-up.
16 affiliations
- 1Department of Orthopedic Surgery, Peking Union Medical College, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, No. 1 Shuaifuyuan, Beijing, 100730, People's Republic of China.
- 2State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, People's Republic of China.
- 3Beijing Key Laboratory for Genetic Research of Skeletal Deformity, Beijing, 100730, People's Republic of China.
- 4Key Laboratory of Big Data for Spinal Deformities, Chinese Academy of Medical Sciences, Beijing, 100730, People's Republic of China.
- 5Department of spine surgery, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, xinjiang, 830001, People's Republic of China.
- 6Medical Research Center, Peking Union Medical College, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.
- 7Department of Orthopedic Surgery, Peking Union Medical College, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, No. 1 Shuaifuyuan, Beijing, 100730, People's Republic of China. [email protected].
- 8Department of Orthopedic Surgery, Peking Union Medical College, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, No. 1 Shuaifuyuan, Beijing, 100730, People's Republic of China. [email protected].
- 9State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, People's Republic of China. [email protected].
- 10Beijing Key Laboratory for Genetic Research of Skeletal Deformity, Beijing, 100730, People's Republic of China. [email protected].
- 11Key Laboratory of Big Data for Spinal Deformities, Chinese Academy of Medical Sciences, Beijing, 100730, People's Republic of China. [email protected].
- 12Department of Orthopedic Surgery, Peking Union Medical College, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, No. 1 Shuaifuyuan, Beijing, 100730, People's Republic of China. [email protected].
- 13State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, People's Republic of China. [email protected].
- 14Beijing Key Laboratory for Genetic Research of Skeletal Deformity, Beijing, 100730, People's Republic of China. [email protected].
- 15Key Laboratory of Big Data for Spinal Deformities, Chinese Academy of Medical Sciences, Beijing, 100730, People's Republic of China. [email protected].
- 16Wenzhou Medical University, Wenzhou, 325035, Zhejiang, People's Republic of China. [email protected].
Abstract
Background
Adolescent idiopathic scoliosis (AIS) significantly impacts physical appearance and quality of life. This exploratory study aims to investigate potential association between cosmetic parameters and minimal clinical improvement in SRS-22r scores at a 2-year follow-up in AIS patients.Methods
A total of 79 patients were included. Data, including the SRS-22r questionnaire and cosmetic parameters were systematically collected pre- and at 2-year follow-ups. Patients were divided into subgroups based on the Minimal Clinically Important Difference (MCID) values for different domains of the SRS-22r, including Total Improved (TI) and Non-Improved (TNI), Function Improved (FI) and Non-Improved (FNI), Self-image Improved (SI) and Non-Improved (SNI), Pain Improved (PI) and Non-Improved (PNI). Cosmetic corrections (p < 0.05) were included in multivariate regression to explore potential associations with SRS-22r improvement.Results
Significant differences in Medial Shoulder Tilt (MS), Lateral Shoulder Tilt (LS), Neck Angle (NA), Angle of Trunk Rotation (ATR), Scapula Asymmetry (SA), Waistline Depth Difference (WD), and Waistline Height Distance (WH) were observed pre- and postoperatively. The "TI" subgroup showed higher MS correction (1.63 ± 3.17°) than the "TNI" subgroup (0.38 ± 1.74°, p = 0.041). The "FI" subgroup showed greater ATR correction (4.82 ± 2.83°) than the "FNI" subgroup (2.82 ± 3.45°, p = 0.008). WD correction was higher in the "PI" subgroup (6.65 ± 8.58 mm) than in the "PNI" subgroup (1.93 ± 5.95 mm, p = 0.025). Logistic regression analysis suggested that, in this exploratory model, MS correction was associated with total domain improvement (OR = 1.240, p = 0.037), ATR correction was associated with function domian improvement (OR = 1.204, p = 0.022), and WD correction was associated with pain domain improvement (OR = 1.098, p = 0.017).Conclusions
In addition to shoulder balance, spinal rotation and waistline asymmetry represent exploratory factors associated with SRS-22r improvement. These findings are hypothesis-generating, as the overall cohort did not achieve MCID thresholds; subgroup analyses explored responder characteristics rather than population-level efficacy.
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BibTeX
@article{maheshati2026cosmetic,
title = {{Cosmetic parameters associated with SRS-22r improvement postoperatively in patients with adolescent idiopathic scoliosis: a 2-year follow-up.}},
author = {Aoran Maheshati and Zhengye Zhao and Xueyi Zhang and Di Liu and Guilin Chen and Ziquan Li and Kexin Xu and Qing Li and Baozhong Zhang and Terry Jianguo Zhang and Nan Wu},
journal = {Journal of orthopaedic surgery and research},
year = {2026},
month = aug,
doi = {10.1186/s13018-026-07086-7},
url = {https://europepmc.org/article/MED/42972391},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Cosmetic parameters associated with SRS-22r improvement postoperatively in patients with adolescent idiopathic scoliosis: a 2-year follow-up.
AU - Aoran Maheshati
AU - Zhengye Zhao
AU - Xueyi Zhang
AU - Di Liu
AU - Guilin Chen
AU - Ziquan Li
AU - Kexin Xu
AU - Qing Li
AU - Baozhong Zhang
AU - Terry Jianguo Zhang
AU - Nan Wu
PY - 2026
DA - 2026/08/05
JO - Journal of orthopaedic surgery and research
DO - 10.1186/s13018-026-07086-7
UR - https://europepmc.org/article/MED/42972391
AB - Background Adolescent idiopathic scoliosis (AIS) significantly impacts physical appearance and quality of life. This exploratory study aims to investigate potential association between cosmetic parameters and minimal clinical improvement in SRS-22r scores at a 2-year follow-up in AIS patients.Methods A total of 79 patients were included. Data, including the SRS-22r questionnaire and cosmetic parameters were systematically collected pre- and at 2-year follow-ups. Patients were divided into subgroups based on the Minimal Clinically Important Difference (MCID) values for different domains of the SRS-22r, including Total Improved (TI) and Non-Improved (TNI), Function Improved (FI) and Non-Improved (FNI), Self-image Improved (SI) and Non-Improved (SNI), Pain Improved (PI) and Non-Improved (PNI). Cosmetic corrections (p < 0.05) were included in multivariate regression to explore potential associations with SRS-22r improvement.Results Significant differences in Medial Shoulder Tilt (MS), Lateral Shoulder Tilt (LS), Neck Angle (NA), Angle of Trunk Rotation (ATR), Scapula Asymmetry (SA), Waistline Depth Difference (WD), and Waistline Height Distance (WH) were observed pre- and postoperatively. The "TI" subgroup showed higher MS correction (1.63 ± 3.17°) than the "TNI" subgroup (0.38 ± 1.74°, p = 0.041). The "FI" subgroup showed greater ATR correction (4.82 ± 2.83°) than the "FNI" subgroup (2.82 ± 3.45°, p = 0.008). WD correction was higher in the "PI" subgroup (6.65 ± 8.58 mm) than in the "PNI" subgroup (1.93 ± 5.95 mm, p = 0.025). Logistic regression analysis suggested that, in this exploratory model, MS correction was associated with total domain improvement (OR = 1.240, p = 0.037), ATR correction was associated with function domian improvement (OR = 1.204, p = 0.022), and WD correction was associated with pain domain improvement (OR = 1.098, p = 0.017).Conclusions In addition to shoulder balance, spinal rotation and waistline asymmetry represent exploratory factors associated with SRS-22r improvement. These findings are hypothesis-generating, as the overall cohort did not achieve MCID thresholds; subgroup analyses explored responder characteristics rather than population-level efficacy.
SN - 1749-799X
ER -