Peer-reviewedCC BY-NC-NDInternal Medicine
A Cerebral Tumor Embolism from Colorectal Cancer via a Patent Foramen Ovale: A Diagnosis Made by Mechanical Thrombectomy
Abstract
A 56-year-old woman presented with an acute cerebral embolism. Mechanical thrombectomy retrieved a white embolus, and a pathological examination revealed a tumor fragment consistent with colorectal carcinoma. Imaging revealed no liver or lung metastases, but it identified a patent foramen ovale and pulmonary embolism, suggesting a paradoxical embolic pathway. Given the size of the tumor fragment, passage through the hepatic or pulmonary microcirculation would be difficult to explain given the size of the tumor fragment. These findings suggest venous invasion with direct entry of tumor material into the circulation, followed by right-to-left shunting, which resulted in a cerebral embolism.
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BibTeX
@article{kobayashi2026cerebral,
title = {{A Cerebral Tumor Embolism from Colorectal Cancer via a Patent Foramen Ovale: A Diagnosis Made by Mechanical Thrombectomy}},
author = {Yuya Kobayashi and Nobuhiko Ohashi and Yasufumi Kondo and Kanji Yamamoto and Hiroshi Suzuki and Yukiko Kusama and Yoshiki Sekijima},
journal = {Internal Medicine},
year = {2026},
month = oct,
doi = {10.2169/internalmedicine.7927-26},
url = {https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7927-26/_article},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - A Cerebral Tumor Embolism from Colorectal Cancer via a Patent Foramen Ovale: A Diagnosis Made by Mechanical Thrombectomy
AU - Yuya Kobayashi
AU - Nobuhiko Ohashi
AU - Yasufumi Kondo
AU - Kanji Yamamoto
AU - Hiroshi Suzuki
AU - Yukiko Kusama
AU - Yoshiki Sekijima
PY - 2026
DA - 2026/10/08
JO - Internal Medicine
DO - 10.2169/internalmedicine.7927-26
UR - https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7927-26/_article
AB - A 56-year-old woman presented with an acute cerebral embolism. Mechanical thrombectomy retrieved a white embolus, and a pathological examination revealed a tumor fragment consistent with colorectal carcinoma. Imaging revealed no liver or lung metastases, but it identified a patent foramen ovale and pulmonary embolism, suggesting a paradoxical embolic pathway. Given the size of the tumor fragment, passage through the hepatic or pulmonary microcirculation would be difficult to explain given the size of the tumor fragment. These findings suggest venous invasion with direct entry of tumor material into the circulation, followed by right-to-left shunting, which resulted in a cerebral embolism.
SN - 1349-7235
SN - 0918-2918
ER -