Organization of duplicated copies of the Arabidopsis gene orthologs AtTT2 and AtTT8 in the allotetraploid cotton genome
- 1N.I. Vavilov All-Russian Institute of Plant Genetic Resources
Abstract
Arabidopsis thaliana L. is a classic model organism in which the regulatory mechanisms of flavonoid pigment biosynthesis involving the AtTT2 gene (R2R3-MYB family) and AtTT8 (bHLH-MYC family) have been characterized in detail. The fate of duplicated copies in allopolyploid species that arose as a result of interspecific hybridization remains a topical question, and cotton Gossypium hirsutum L. provides a convenient model to address it. In the genome of G. hirsutum, copies of the genes GhTT2, GhMYB10, and GhTT8 have been identified in the At- and Dt-subgenomes; these copies are orthologs of the corresponding A. thaliana genes. Based on the sequencing of alleles of these regulatory genes in cotton accessions with contrasting fiber and hypocotyl pigmentation, this study evaluates the role of allopolyploidization in the evolution of duplicated regulatory genes encoding components of the MBW complex, namely R2R3-MYB, bHLH-MYC, and WD40 transcription factors. The cotton R2R3-MYB gene family has been found to evolve asymmetrically, when genes of the At subgenome evolve faster and are subject to a less stringent purifying selection compared to their homeologs in the Dt subgenome. It is for the first time that the gene sequences were deposited in the international GenBank database (NCBI).
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BibTeX
@article{mikhailova2026organization,
title = {{Organization of duplicated copies of the Arabidopsis gene orthologs AtTT2 and AtTT8 in the allotetraploid cotton genome}},
author = {A. S. Mikhailova and E. K. Khlestkina},
journal = {Биотехнология и селекция растений},
year = {2026},
month = sep,
doi = {10.30901/2658-6266-2026-3-o1},
url = {https://doi.org/10.30901/2658-6266-2026-3-o1},
note = {CC BY},
}
RIS
TY - JOUR
TI - Organization of duplicated copies of the Arabidopsis gene orthologs AtTT2 and AtTT8 in the allotetraploid cotton genome
AU - A. S. Mikhailova
AU - E. K. Khlestkina
PY - 2026
DA - 2026/09/01
JO - Биотехнология и селекция растений
DO - 10.30901/2658-6266-2026-3-o1
UR - https://doi.org/10.30901/2658-6266-2026-3-o1
AB - Arabidopsis thaliana L. is a classic model organism in which the regulatory mechanisms of flavonoid pigment biosynthesis involving the AtTT2 gene (R2R3-MYB family) and AtTT8 (bHLH-MYC family) have been characterized in detail. The fate of duplicated copies in allopolyploid species that arose as a result of interspecific hybridization remains a topical question, and cotton Gossypium hirsutum L. provides a convenient model to address it. In the genome of G. hirsutum, copies of the genes GhTT2, GhMYB10, and GhTT8 have been identified in the At- and Dt-subgenomes; these copies are orthologs of the corresponding A. thaliana genes. Based on the sequencing of alleles of these regulatory genes in cotton accessions with contrasting fiber and hypocotyl pigmentation, this study evaluates the role of allopolyploidization in the evolution of duplicated regulatory genes encoding components of the MBW complex, namely R2R3-MYB, bHLH-MYC, and WD40 transcription factors. The cotton R2R3-MYB gene family has been found to evolve asymmetrically, when genes of the At subgenome evolve faster and are subject to a less stringent purifying selection compared to their homeologs in the Dt subgenome. It is for the first time that the gene sequences were deposited in the international GenBank database (NCBI).
SN - 2658-6266
SN - 2658-6258
ER -