Skip to content
DraconiticResearch
Search Sources API
194,164 studies31 sourcesUpdated 55 min ago
PreprintCC BYbioRxiv

Living representatives of the spiralian ancestral karyotype revealed by two Lima genomes

  • F. Denoeud1
  • B. Istace
  • Y. Dussert
  • J.-M. Aury
  1. 1Genoscope, CEA Institut de Genomique
Read full textPDFDOICite

Abstract

Conserved synteny enables the reconstruction of ancestral chromosome organization across deeply diverged lineages, as demonstrated across metazoans. In Spiralia, comparative genomic analyses have suggested an ancestral karyotype comprising 20 chromosomes. We report high-quality genome assemblies for two Lima species (Lima caribaea and Lima lima) with 20 chromosomes and show that their chromosome organization matches this ancestral state, including four previously described fusion-with-mixing events. Interestingly, other Limidae genus did not retain the ancestral karyotype: they have undergone subsequent lineage-specific fusions. The conserved organization of Lima chromosomes provides a rare genomic anchor for reconstructing ancestral chromosome organization and lineage-specific chromosome evolution across Spiralia and, more broadly, Metazoa.

Related

  1. Ancestral Karyotype Reconstruction Reveals Chromosome Rearrangements and Large Inversions in Oryza
    Qiang Xu, Meifang Lan, Ying Chen +5
    Plants (Basel, Switzerland)Peer-reviewedCC BYFull textPlant biologyEurope PMC
  2. Reconstruction of the gastropod ancestral karyotype reveals lineage-specific chromosomal evolution and adaptations during habitat transitions
    Z. Zhong, Y. Zhou, H. Wang +3
    bioRxivPreprintCC BY-NCFull textEvolutionary biologybioRxiv
  3. Barking Up Inferred Trees: Detecting Signatures of Selection in Dog Genomes Using Ancestral Recombination Graphs
    J. M. Kidd
    bioRxivPreprintCC BY-NCFull textEvolutionary biologybioRxiv
  4. Reconstruction of ancestral plant genomes for inter-crop translational research
    Cléa Siguret, Margaux Olivier, Cécile Huneau +17
    Molecular PlantPeer-reviewedCC BY-NC-ND 4.0Full text1 citedBioinformatics & computational biologyEcologyHAL
  5. Molecular fossils of an ancestral code revealed by large-scale analysis of tRNAs
    Ash Nova Royo, Paula Martín-Cabezas, Sergey Ovchinnikov +2
    Proceedings of the National Academy of Sciences of the United States of AmericaPeer-reviewedCC BY-NC-ND 4.0Full textEvolutionary biologyPMC

Cite

BibTeXRIS
BibTeX
@misc{denoeud2026living,
  title = {{Living representatives of the spiralian ancestral karyotype revealed by two Lima genomes}},
  author = {F. Denoeud and B. Istace and Y. Dussert and J.-M. Aury},
  howpublished = {bioRxiv},
  year = {2026},
  month = oct,
  doi = {10.64898/2026.10.09.757954},
  url = {https://www.biorxiv.org/content/10.64898/2026.10.09.757954v1},
  note = {CC BY},
}
RIS
TY  - UNPB
TI  - Living representatives of the spiralian ancestral karyotype revealed by two Lima genomes
AU  - F. Denoeud
AU  - B. Istace
AU  - Y. Dussert
AU  - J.-M. Aury
PY  - 2026
DA  - 2026/10/09
PB  - bioRxiv
DO  - 10.64898/2026.10.09.757954
UR  - https://www.biorxiv.org/content/10.64898/2026.10.09.757954v1
AB  - Conserved synteny enables the reconstruction of ancestral chromosome organization across deeply diverged lineages, as demonstrated across metazoans. In Spiralia, comparative genomic analyses have suggested an ancestral karyotype comprising 20 chromosomes. We report high-quality genome assemblies for two Lima species (Lima caribaea and Lima lima) with 20 chromosomes and show that their chromosome organization matches this ancestral state, including four previously described fusion-with-mixing events. Interestingly, other Limidae genus did not retain the ancestral karyotype: they have undergone subsequent lineage-specific fusions. The conserved organization of Lima chromosomes provides a rare genomic anchor for reconstructing ancestral chromosome organization and lineage-specific chromosome evolution across Spiralia and, more broadly, Metazoa.
ER  -