Adsorption of the low density lipoproteins on the micropatterned polymer brush: computer simulations
Abstract
Photorenewable polymer adsorbents, aimed at reducing the low density lipoproteins (LDLs) level, are reported experimentally. Previously we developed a mesoscale model for this setup with uniformly grafted chains, and examined the role played by chains length and grafting density [Ilnytskyi, et al., Processes, 2023, 11, 2913]. The analysis is extended here to the cases of bunch-like and grid-like grafting micropatterns. The bunch-like arrangement is the most efficient one displaying low- and high-density peaks for adsorbing effectiveness. The former peak is twice higher compared with uniform grafting, as a consequence of a match between LDLs dimensions and the micropattern pitch. Adsorption isotherms are fitted well by either Langmuir or logistic growth forms, indicating a higher growth rate compared with uniform grafting. The high-density peak exists only for this micropattern and extends the applicability of an adsorbent. At the highest LDL concentration, adsorption is hampered by self-assembly of LDLs into a packed cubic phase.
Versions
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BibTeX
@misc{ilnytskyi2026adsorption,
title = {{Adsorption of the low density lipoproteins on the micropatterned polymer brush: computer simulations}},
author = {J. Ilnytskyi and D. Yaremchuk and O. Komarytsia},
howpublished = {arXiv},
year = {2026},
month = sep,
doi = {10.48550/arxiv.2609.26613},
eprint = {2609.26613},
archivePrefix = {arXiv},
url = {https://arxiv.org/abs/2609.26613},
note = {CC BY 4.0},
}
RIS
TY - UNPB
TI - Adsorption of the low density lipoproteins on the micropatterned polymer brush: computer simulations
AU - J. Ilnytskyi
AU - D. Yaremchuk
AU - O. Komarytsia
PY - 2026
DA - 2026/09/29
PB - arXiv
DO - 10.48550/arxiv.2609.26613
UR - https://arxiv.org/abs/2609.26613
AB - Photorenewable polymer adsorbents, aimed at reducing the low density lipoproteins (LDLs) level, are reported experimentally. Previously we developed a mesoscale model for this setup with uniformly grafted chains, and examined the role played by chains length and grafting density [Ilnytskyi, et al., Processes, 2023, 11, 2913]. The analysis is extended here to the cases of bunch-like and grid-like grafting micropatterns. The bunch-like arrangement is the most efficient one displaying low- and high-density peaks for adsorbing effectiveness. The former peak is twice higher compared with uniform grafting, as a consequence of a match between LDLs dimensions and the micropattern pitch. Adsorption isotherms are fitted well by either Langmuir or logistic growth forms, indicating a higher growth rate compared with uniform grafting. The high-density peak exists only for this micropattern and extends the applicability of an adsorbent. At the highest LDL concentration, adsorption is hampered by self-assembly of LDLs into a packed cubic phase.
ER -