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Peer-reviewedCC BY 4.0Frontiers in Cardiovascular Medicine

Analysis of risk factors for kinesiophobia after coronary artery bypass grafting and construction of a nomogram prediction model

  1. 1Cardiac and Vascular Surgery ICU, The First Affiliated Hospital of Anhui Medical University
  2. 2Department of Cardiovascular Medicine, The First Affiliated Hospital of Anhui Medical University

Abstract

Background: Kinesiophobia, or the irrational fear of movement, is a significant barrier to effective cardiac rehabilitation and recovery in patients after coronary artery bypass grafting (CABG). This study sought to identify the risk factors for kinesiophobia in post-CABG patients and to develop and validate a nomogram prediction model to estimate individual risk.

Methods: A retrospective case-control study was conducted on 138 patients who underwent CABG in the Cardiovascular ICU between February 2023 and November 2024. Using the Tampa Scale for Kinesiophobia-Heart (TSK-Heart), patients were categorized into a kinesiophobia group (TSK-Heart >37, n = 95) and a non-kinesiophobia group ( n = 43). Risk Factors were identified with multivariable logistic regression. The resulting coefficients furnished a nomogram for individual risk estimation. Calibration was evaluated with the Hosmer-Lemeshow test and a bootstrap-corrected calibration plot; discrimination was quantified by the receiver operating characteristic (ROC) curve and calibration curve.

Results: The incidence of kinesiophobia in this cohort was 68.84%. The logistic regression analysis identified six risk factors: advanced age ( OR = 1.127, P = 0.003), lower educational level ( OR = 0.246, P = 0.001), higher degree of disability in activities of daily living (ADL) ( OR = 3.880, P = 0.007), lower self-efficacy in cardiac rehabilitation exercise ( OR = 0.898, P = 0.024), pain catastrophizing ( OR = 4.513, P = 0.023), and fear of falling ( OR = 1.212, P = 0.004). The constructed nomogram demonstrated excellent discrimination, with an AUC of 0.939 (95% CI : 0.898–0.981), and high sensitivity (93.7%) and specificity (83.7%). Calibration was confirmed by the Hosmer-Lemeshow test ( χ ² = 5.97, P = 0.65) and a bootstrap-corrected calibration plot showing close agreement between predicted and observed probabilities.

Conclusions: Advanced age, low educational attainment, ADL dependency, poor cardiac rehabilitation self-efficacy, pain catastrophizing, and fear of falling were significant risk factors for kinesiophobia after CABG. The developed nomogram was a reliable and accurate tool for early identification of high-risk patients, enabling clinicians to implement individualized preventative strategies and optimize postoperative recovery.

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BibTeX
@article{guo2026analysis,
  title = {{Analysis of risk factors for kinesiophobia after coronary artery bypass grafting and construction of a nomogram prediction model}},
  author = {Lancai Guo and Jing Li and Wenjuan Ye and Xue Wei and Xia Wu and Xiaocan Wang},
  journal = {Frontiers in Cardiovascular Medicine},
  year = {2026},
  month = oct,
  doi = {10.3389/fcvm.2026.1742685},
  url = {https://www.frontiersin.org/articles/10.3389/fcvm.2026.1742685/full},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Analysis of risk factors for kinesiophobia after coronary artery bypass grafting and construction of a nomogram prediction model
AU  - Lancai Guo
AU  - Jing Li
AU  - Wenjuan Ye
AU  - Xue Wei
AU  - Xia Wu
AU  - Xiaocan Wang
PY  - 2026
DA  - 2026/10/26
JO  - Frontiers in Cardiovascular Medicine
DO  - 10.3389/fcvm.2026.1742685
UR  - https://www.frontiersin.org/articles/10.3389/fcvm.2026.1742685/full
AB  - Background: Kinesiophobia, or the irrational fear of movement, is a significant barrier to effective cardiac rehabilitation and recovery in patients after coronary artery bypass grafting (CABG). This study sought to identify the risk factors for kinesiophobia in post-CABG patients and to develop and validate a nomogram prediction model to estimate individual risk.  Methods: A retrospective case-control study was conducted on 138 patients who underwent CABG in the Cardiovascular ICU between February 2023 and November 2024. Using the Tampa Scale for Kinesiophobia-Heart (TSK-Heart), patients were categorized into a kinesiophobia group (TSK-Heart >37, n = 95) and a non-kinesiophobia group ( n = 43). Risk Factors were identified with multivariable logistic regression. The resulting coefficients furnished a nomogram for individual risk estimation. Calibration was evaluated with the Hosmer-Lemeshow test and a bootstrap-corrected calibration plot; discrimination was quantified by the receiver operating characteristic (ROC) curve and calibration curve.  Results: The incidence of kinesiophobia in this cohort was 68.84%. The logistic regression analysis identified six risk factors: advanced age ( OR = 1.127, P = 0.003), lower educational level ( OR = 0.246, P = 0.001), higher degree of disability in activities of daily living (ADL) ( OR = 3.880, P = 0.007), lower self-efficacy in cardiac rehabilitation exercise ( OR = 0.898, P = 0.024), pain catastrophizing ( OR = 4.513, P = 0.023), and fear of falling ( OR = 1.212, P = 0.004). The constructed nomogram demonstrated excellent discrimination, with an AUC of 0.939 (95% CI : 0.898–0.981), and high sensitivity (93.7%) and specificity (83.7%). Calibration was confirmed by the Hosmer-Lemeshow test ( χ ² = 5.97, P = 0.65) and a bootstrap-corrected calibration plot showing close agreement between predicted and observed probabilities.  Conclusions: Advanced age, low educational attainment, ADL dependency, poor cardiac rehabilitation self-efficacy, pain catastrophizing, and fear of falling were significant risk factors for kinesiophobia after CABG. The developed nomogram was a reliable and accurate tool for early identification of high-risk patients, enabling clinicians to implement individualized preventative strategies and optimize postoperative recovery.
SN  - 2297-055X
ER  -