Skip to content
DraconiticResearch
Search Sources API
197,768 studies31 sourcesUpdated 27 min ago
Peer-reviewedCC BY 4.0Journal of Clinical Ultrasound

Ultrasound Findings in Symptomatic HADD of the Hand and Wrist. A Case Series of 37 Patients

  • Marco Becciolini1,2
  • Riccardo Picasso3
  • Antonio Corvino4
  • Federico Zaottini3,5
5 affiliations
  1. 1Misericordia di Pistoia Pistoia Italy
  2. 2Scuola Siumb di Ecografia Muscolo‐Scheletrica Pisa Italy
  3. 3Division of Radiology IRCCS Azienda Ospedaliera Metropolitana, Ospedale Policlinico San Martino Genova Italy
  4. 4Medical, Movement and Wellbeing Sciences Department University of Naples “Parthenope” Naples Italy
  5. 5Department of Health Sciences (DISSAL) University of Genova Genova Italy
Read full textDOICite

Abstract

Purpose: To present a series of 37 cases diagnosed with ultrasound (US) of symptomatic hydroxyapatite deposition disease (HADD) involving the wrist and hand.

Materials and Methods: Reports from two institutions were searched using the keywords “HADD hand/wrist” or “calcium deposit hand/wrist”. The US examinations were performed with a similar standardized approach, focusing on the region of pain. B‐mode and Doppler sonograms were acquired. Each author reviewed the cases to ensure that only cases consistent with HADD were included.

Results: A total of 37 patients were identified, mostly women (81% of the cases). The mean age was 50 years old. Calcifications usually showed resorptive stage features (type III). Follow‐up clinical data were available in 16 patients, mostly with at least a partial resolution of symptoms.

Conclusion: US is a useful imaging technique to diagnose HADD of the hand and wrist, especially in the correct clinical context (e.g., acute non‐traumatic symptoms in women, with progressive improvement in pain). Conventional radiography may help to confirm the calcific deposit. Advanced imaging modalities are usually not required, but may be considered in selected cases. Follow‐up to confirm an improvement over time is suggested.

Related

  1. Five-Year Outcomes of Transcatheter Mitral Valve Replacement in Patients With Severe Symptomatic Mitral Regurgitation: Results From the Tendyne Expanded Clinical Study
    David W Muller, Alison Duncan, Paul Sorajja +25
    ESC Heart FailurePeer-reviewedCC BY 4.0Full textSystems & synthetic biologyHAL
  2. Chromodomain Helicase DNA-Binding Domain 8 (CHD8) related neurodevelopmental disorder with overgrowth: a case series and a systematic literature review on neuroradiological findings
    Leonie Zerweck, Kathrin Grundmann-Hauser, Christiane Kehrer +13
    Journal of Rare DiseasesPeer-reviewedCC BYFull textGenetics & genomicsDOAJ
  3. Safety of lecanemab in real-world patients with Alzheimer’s disease: a prospective, observational case series supported by FAERS signal analysis
    Haixia Ji, Yang Yang, Xingqi Wu +1
    Frontiers in neuroinformaticsPeer-reviewedCC BYFull textNeuroscienceEurope PMC
  4. Clinical Manifestations and Genetic Findings in Three Patients with Chediak-Higashi Syndrome: Highlighting the Splice Site Variants
    Shaghayegh Tajik, Anne Molitor, Zahra Alizadeh +8
    Iranian Journal of Allergy, Asthma and ImmunologyPeer-reviewedCC BY-NC 4.0Full textImmunologyHAL
  5. Serial ultrasound assessment of flexor carpi ulnaris and biceps brachii cross-sectional area in critically ill patients: A prospective cohort study
    Keiichiro Aoki, Fumihito Kasai, Kazuki Komaba +6
    PLOS OnePeer-reviewedCC BYFull textGeneral biologyMedical imaging & radiologyPLOSEurope PMCPMC

Cite

BibTeXRIS
BibTeX
@article{becciolini2026ultrasound,
  title = {{Ultrasound Findings in Symptomatic HADD of the Hand and Wrist. A Case Series of 37 Patients}},
  author = {Marco Becciolini and Riccardo Picasso and Antonio Corvino and Federico Zaottini},
  journal = {Journal of Clinical Ultrasound},
  year = {2026},
  month = jul,
  doi = {10.1002/jcu.70312},
  url = {https://doi.org/10.1002/jcu.70312},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Ultrasound Findings in Symptomatic HADD of the Hand and Wrist. A Case Series of 37 Patients
AU  - Marco Becciolini
AU  - Riccardo Picasso
AU  - Antonio Corvino
AU  - Federico Zaottini
PY  - 2026
DA  - 2026/07/13
JO  - Journal of Clinical Ultrasound
DO  - 10.1002/jcu.70312
UR  - https://doi.org/10.1002/jcu.70312
AB  - Purpose: To present a series of 37 cases diagnosed with ultrasound (US) of symptomatic hydroxyapatite deposition disease (HADD) involving the wrist and hand.  Materials and Methods: Reports from two institutions were searched using the keywords “HADD hand/wrist” or “calcium deposit hand/wrist”. The US examinations were performed with a similar standardized approach, focusing on the region of pain. B‐mode and Doppler sonograms were acquired. Each author reviewed the cases to ensure that only cases consistent with HADD were included.  Results: A total of 37 patients were identified, mostly women (81% of the cases). The mean age was 50 years old. Calcifications usually showed resorptive stage features (type III). Follow‐up clinical data were available in 16 patients, mostly with at least a partial resolution of symptoms.  Conclusion: US is a useful imaging technique to diagnose HADD of the hand and wrist, especially in the correct clinical context (e.g., acute non‐traumatic symptoms in women, with progressive improvement in pain). Conventional radiography may help to confirm the calcific deposit. Advanced imaging modalities are usually not required, but may be considered in selected cases. Follow‐up to confirm an improvement over time is suggested.
SN  - 0091-2751
SN  - 1097-0096
ER  -