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Peer-reviewedCC BY-NC-ND 4.0Poultry Science

Consideration of mineral homeostasis when conducting calcium nutrition work in poultry

  1. 1Department of Poultry Science, University of Georgia, Athens, GA, USA

Abstract

Optimal dietary calcium levels are necessary for efficient growth, bone mineralization, and eggshell calcification in poultry. To properly assess nutritional requirements at all physiological stages, a holistic understanding of mechanisms governing both calcium and phosphorus homeostasis is necessary. Intestinal uptake, renal reabsorption and excretion, and bone remodeling of both minerals involve the integrated action of bioactive 1,25-dihydroxycholecalciferol, parathyroid hormone, calcitonin, and fibroblast growth factor 23 on the intestine, kidney, and bone. In laying hens, eggshell calcification imposes additional demands on these systems. Hormonal regulation of intestinal and renal calcium and phosphorus transporter expression and activity is highly dependent on vitamin D3 status, in addition to both absolute and relative dietary levels of calcium and phosphorus. This symposium paper will provide an overview of the regulatory systems governing calcium homeostasis, with a particular focus on hormonal regulation, intestinal uptake, and aspects of laying hen physiology that must be considered when designing calcium nutrition studies and interpreting findings in a meaningful way.

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BibTeX
@article{ellestad2026consideration,
  title = {{Consideration of mineral homeostasis when conducting calcium nutrition work in poultry}},
  author = {Laura E. Ellestad and Micaela Sinclair-Black and R. Alejandra Garcia-Mejia},
  journal = {Poultry Science},
  year = {2026},
  month = oct,
  doi = {10.1016/j.psj.2026.108003},
  url = {https://doi.org/10.1016/j.psj.2026.108003},
  note = {CC BY-NC-ND 4.0},
}
RIS
TY  - JOUR
TI  - Consideration of mineral homeostasis when conducting calcium nutrition work in poultry
AU  - Laura E. Ellestad
AU  - Micaela Sinclair-Black
AU  - R. Alejandra Garcia-Mejia
PY  - 2026
DA  - 2026/10/21
JO  - Poultry Science
DO  - 10.1016/j.psj.2026.108003
UR  - https://doi.org/10.1016/j.psj.2026.108003
AB  - Optimal dietary calcium levels are necessary for efficient growth, bone mineralization, and eggshell calcification in poultry. To properly assess nutritional requirements at all physiological stages, a holistic understanding of mechanisms governing both calcium and phosphorus homeostasis is necessary. Intestinal uptake, renal reabsorption and excretion, and bone remodeling of both minerals involve the integrated action of bioactive 1,25-dihydroxycholecalciferol, parathyroid hormone, calcitonin, and fibroblast growth factor 23 on the intestine, kidney, and bone. In laying hens, eggshell calcification imposes additional demands on these systems. Hormonal regulation of intestinal and renal calcium and phosphorus transporter expression and activity is highly dependent on vitamin D3 status, in addition to both absolute and relative dietary levels of calcium and phosphorus. This symposium paper will provide an overview of the regulatory systems governing calcium homeostasis, with a particular focus on hormonal regulation, intestinal uptake, and aspects of laying hen physiology that must be considered when designing calcium nutrition studies and interpreting findings in a meaningful way.
SN  - 0032-5791
SN  - 1525-3171
ER  -