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Peer-reviewedCC BY 4.0Journal of Clinical Ultrasound

Complicated Acute Appendicitis Conservatively Treated in Two Patients With Crohn's Disease: The Role of Intestinal Ultrasound and Contrast‐Enhanced Ultrasound

  • Cataletti Giovanni1
  • Gridavilla Daniele1
  • Nylund Kim2,3
  • Colombo Francesco4
  • Danelli Piergiorgio4
  • Maconi Giovanni1
4 affiliations
  1. 1Gastroenterology Unit, Department of Biomedical and Clinical Sciences “L. Sacco” Hospital, University of Milano Milan Italy
  2. 2National Centre for Ultrasound in Gastroenterology, Haukeland University Hospital Bergen Norway
  3. 3Department of Clinical Medicine University of Bergen Bergen Norway
  4. 4Division of General Surgery, Department of Biomedical and Clinical Sciences “L. Sacco” Hospital, University of Milano Milan Italy
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Abstract

According to the most recent guidelines, uncomplicated acute appendicitis could be treated conservatively using broad‐spectrum antibiotics, but if radiological signs of appendix rupture are present, appendectomy should be considered as first‐line treatment. There is limited evidence in literature regarding the non‐operative management of complicated acute appendicitis, particularly in the subset of patients with Crohn's disease. Intestinal and contrast‐enhanced ultrasound appear pivotal to both diagnosing complications and promptly identifying the non‐responding patients. We describe two cases of complicated acute appendicitis, successfully treated with broad‐spectrum antibiotic therapy and tight monitoring with both intestinal and contrast‐enhanced ultrasound, in patients with Crohn's disease.

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Cite

BibTeXRIS
BibTeX
@article{giovanni2026complicated,
  title = {{Complicated Acute Appendicitis Conservatively Treated in Two Patients With Crohn's Disease: The Role of Intestinal Ultrasound and Contrast‐Enhanced Ultrasound}},
  author = {Cataletti Giovanni and Gridavilla Daniele and Nylund Kim and Colombo Francesco and Danelli Piergiorgio and Maconi Giovanni},
  journal = {Journal of Clinical Ultrasound},
  year = {2026},
  month = jun,
  doi = {10.1002/jcu.70288},
  url = {https://doi.org/10.1002/jcu.70288},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Complicated Acute Appendicitis Conservatively Treated in Two Patients With Crohn's Disease: The Role of Intestinal Ultrasound and Contrast‐Enhanced Ultrasound
AU  - Cataletti Giovanni
AU  - Gridavilla Daniele
AU  - Nylund Kim
AU  - Colombo Francesco
AU  - Danelli Piergiorgio
AU  - Maconi Giovanni
PY  - 2026
DA  - 2026/06/17
JO  - Journal of Clinical Ultrasound
DO  - 10.1002/jcu.70288
UR  - https://doi.org/10.1002/jcu.70288
AB  - According to the most recent guidelines, uncomplicated acute appendicitis could be treated conservatively using broad‐spectrum antibiotics, but if radiological signs of appendix rupture are present, appendectomy should be considered as first‐line treatment. There is limited evidence in literature regarding the non‐operative management of complicated acute appendicitis, particularly in the subset of patients with Crohn's disease. Intestinal and contrast‐enhanced ultrasound appear pivotal to both diagnosing complications and promptly identifying the non‐responding patients. We describe two cases of complicated acute appendicitis, successfully treated with broad‐spectrum antibiotic therapy and tight monitoring with both intestinal and contrast‐enhanced ultrasound, in patients with Crohn's disease.
SN  - 0091-2751
SN  - 1097-0096
ER  -