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Peer-reviewedCC BY 4.0Frontiers in Plant Science

The potato (Solanum tuberosum L.) transcription factor StPHR1 responds to low phosphate stress and regulates phosphorus accumulation

  • Feng Zhang1,2
  • Huaijuan Gou2
  • Yanlin An2
  • Wenlun Wang2
  • Haiyan Zhang3
  1. 1School of Business Administration, Moutai Institute
  2. 2School of Food Engineering, Moutai Institute
  3. 3School of Resources and Environmental Engineering, Moutai Institute
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Abstract

Phosphorus is an essential macronutrient for plant growth and development. Potato is highly sensitive to inorganic phosphate (Pi) availability, yet the function and regulation of StPHR1, a putative core component of plant Pi signaling, remain poorly defined in this crop. Evolutionary analysis, subcellular localization assays, promoter activity analysis, CRISPR/Cas9-mediated gene editing, overexpression, and data-independent acquisition proteomics were used to characterize StPHR1. StPHR1 encoded a nuclear-localized MYB-CC transcription factor, whose promoter exhibits preferential activity in root tips and vascular tissues. Loss of StPHR1 function compromised low-Pi tolerance, reduced Pi accumulation in roots and leaves, and inhibited plant growth, whereas StPHR1 overexpression enhanced low-Pi tolerance and increased both tuber number and average tuber weight under conventional fertilized cultivation. Proteomic profiling showed that StPHR1-dependent Pi starvation responses involve metabolic reprogramming, membrane-lipid remodeling, redox homeostasis, and detoxification. These results identify StPHR1 as a key regulator of Pi accumulation and allocation in potato and provide candidate targets and a molecular framework for improving low-Pi adaptation.

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Cite

BibTeXRIS
BibTeX
@article{zhang2026potato,
  title = {{The potato (Solanum tuberosum L.) transcription factor StPHR1 responds to low phosphate stress and regulates phosphorus accumulation}},
  author = {Feng Zhang and Huaijuan Gou and Yanlin An and Wenlun Wang and Haiyan Zhang},
  journal = {Frontiers in Plant Science},
  year = {2026},
  month = oct,
  doi = {10.3389/fpls.2026.1975545},
  url = {https://www.frontiersin.org/articles/10.3389/fpls.2026.1975545/full},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - The potato (Solanum tuberosum L.) transcription factor StPHR1 responds to low phosphate stress and regulates phosphorus accumulation
AU  - Feng Zhang
AU  - Huaijuan Gou
AU  - Yanlin An
AU  - Wenlun Wang
AU  - Haiyan Zhang
PY  - 2026
DA  - 2026/10/21
JO  - Frontiers in Plant Science
DO  - 10.3389/fpls.2026.1975545
UR  - https://www.frontiersin.org/articles/10.3389/fpls.2026.1975545/full
AB  - Phosphorus is an essential macronutrient for plant growth and development. Potato is highly sensitive to inorganic phosphate (Pi) availability, yet the function and regulation of StPHR1, a putative core component of plant Pi signaling, remain poorly defined in this crop. Evolutionary analysis, subcellular localization assays, promoter activity analysis, CRISPR/Cas9-mediated gene editing, overexpression, and data-independent acquisition proteomics were used to characterize StPHR1. StPHR1 encoded a nuclear-localized MYB-CC transcription factor, whose promoter exhibits preferential activity in root tips and vascular tissues. Loss of StPHR1 function compromised low-Pi tolerance, reduced Pi accumulation in roots and leaves, and inhibited plant growth, whereas StPHR1 overexpression enhanced low-Pi tolerance and increased both tuber number and average tuber weight under conventional fertilized cultivation. Proteomic profiling showed that StPHR1-dependent Pi starvation responses involve metabolic reprogramming, membrane-lipid remodeling, redox homeostasis, and detoxification. These results identify StPHR1 as a key regulator of Pi accumulation and allocation in potato and provide candidate targets and a molecular framework for improving low-Pi adaptation.
SN  - 1664-462X
ER  -