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Peer-reviewedCC BY-NC-NDOpen respiratory archives

[Obstructive Sleep Apnea in Interstitial Lung Disease: an underdiagnosed comorbidity].

  • Francisco León-Román1,2
  • Beatriz Pintado-Cort1
  • Mireia Dalmases3,4
  • Irene Cano-Pumarega4,5,6
  • Cristina Embid3
  • Juan Rigual-Bobillo5
  • Ana Jaureguizar-Oriol5
  • Aldara García-Sánchez4,5,6
  • Claudia Beigveder Durante7
  • Jacobo Sellares3,4
7 affiliations
  1. 1Servicio de Neumología, Hospital Universitario de Burgos, Burgos, España.
  2. 2Medicina e Investigación Traslacional, Universidad de Barcelona, Barcelona, España.
  3. 3Servicio de Neumología, Hospital Clinic Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, España.
  4. 4Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, España.
  5. 5Servicio de Neumología, Hospital Universitario Ramón y Cajal, Madrid, España.
  6. 6Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, España.
  7. 7Servicio de Neumología, Hospital Universitario Río Hortega, Valladolid, España.
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Abstract

Obstructive sleep apnea (OSA) is a common yet underdiagnosed comorbidity that significantly affects the clinical course, quality of life, and prognosis of patients with interstitial lung disease (ILD). The interaction between these two conditions suggests the presence of bidirectional pathophysiological mechanisms. The diagnosis of OSA in this setting is challenging due to symptom overlap and the limitations of currently available screening tools. Regarding the management of OSA in patients with ILD, there are no randomized clinical trials evaluating the use of continuous positive airway pressure (CPAP). This article reviews the available evidence on the pathophysiology, diagnosis, and treatment of OSA in ILD.

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Cite

BibTeXRIS
BibTeX
@article{leonroman2026obstructive,
  title = {{[Obstructive Sleep Apnea in Interstitial Lung Disease: an underdiagnosed comorbidity].}},
  author = {Francisco León-Román and Beatriz Pintado-Cort and Mireia Dalmases and Irene Cano-Pumarega and Cristina Embid and Juan Rigual-Bobillo and Ana Jaureguizar-Oriol and Aldara García-Sánchez and Claudia Beigveder Durante and Jacobo Sellares},
  journal = {Open respiratory archives},
  year = {2026},
  month = sep,
  doi = {10.1016/j.opresp.2026.100676},
  url = {https://europepmc.org/article/MED/42926829},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - [Obstructive Sleep Apnea in Interstitial Lung Disease: an underdiagnosed comorbidity].
AU  - Francisco León-Román
AU  - Beatriz Pintado-Cort
AU  - Mireia Dalmases
AU  - Irene Cano-Pumarega
AU  - Cristina Embid
AU  - Juan Rigual-Bobillo
AU  - Ana Jaureguizar-Oriol
AU  - Aldara García-Sánchez
AU  - Claudia Beigveder Durante
AU  - Jacobo Sellares
PY  - 2026
DA  - 2026/09/19
JO  - Open respiratory archives
DO  - 10.1016/j.opresp.2026.100676
UR  - https://europepmc.org/article/MED/42926829
AB  - Obstructive sleep apnea (OSA) is a common yet underdiagnosed comorbidity that significantly affects the clinical course, quality of life, and prognosis of patients with interstitial lung disease (ILD). The interaction between these two conditions suggests the presence of bidirectional pathophysiological mechanisms. The diagnosis of OSA in this setting is challenging due to symptom overlap and the limitations of currently available screening tools. Regarding the management of OSA in patients with ILD, there are no randomized clinical trials evaluating the use of continuous positive airway pressure (CPAP). This article reviews the available evidence on the pathophysiology, diagnosis, and treatment of OSA in ILD.
SN  - 2659-6636
ER  -