Vaccination status and its association with complications among the patients admitted with measles in the dedicated measles hospitals, Dhaka, Bangladesh

@article{goutam2026vaccination,
  title = {{Vaccination status and its association with complications among the patients admitted with measles in the dedicated measles hospitals, Dhaka, Bangladesh}},
  author = {Arpita Goutam and Anamul Hasan and Md Abdullah Saeed Khan and Mohammad Ali Hossain Mahid and Sumaya Binte Masud and Habiba Babul and Lamisa Rahman and Amina Siddiqui and Salma Tasnim Luthfa and Samiha Nahar Tuli and Indrani Paul and M. Rashidul Bari and Abu Sayeed Md Saleh and Mohammad Delwer Hossain Hawlader},
  journal = {PLOS One},
  year = {2026},
  month = nov,
  doi = {10.1371/journal.pone.0353336},
  url = {https://doi.org/10.1371/journal.pone.0353336},
  note = {CC BY 4.0},
}

TY  - JOUR
TI  - Vaccination status and its association with complications among the patients admitted with measles in the dedicated measles hospitals, Dhaka, Bangladesh
AU  - Arpita Goutam
AU  - Anamul Hasan
AU  - Md Abdullah Saeed Khan
AU  - Mohammad Ali Hossain Mahid
AU  - Sumaya Binte Masud
AU  - Habiba Babul
AU  - Lamisa Rahman
AU  - Amina Siddiqui
AU  - Salma Tasnim Luthfa
AU  - Samiha Nahar Tuli
AU  - Indrani Paul
AU  - M. Rashidul Bari
AU  - Abu Sayeed Md Saleh
AU  - Mohammad Delwer Hossain Hawlader
PY  - 2026
DA  - 2026/11/11
JO  - PLOS One
DO  - 10.1371/journal.pone.0353336
UR  - https://doi.org/10.1371/journal.pone.0353336
AB  - Bangladesh is facing a major resurgence of measles, with more than 60,000 suspected cases and over 600 deaths reported between March and May 2026. Despite the growing outbreak, hospital-based evidence in Bangladesh remains limited regarding measles vaccination status and its association with clinical complications. To address this critical gap, our study aimed to assess the vaccination status and its relationship with the development of clinical complications. This cross-sectional study enrolled 260 children aged 2–72 months with clinically confirmed measles who were admitted to four dedicated measles treatment hospitals in Dhaka, Bangladesh, between 15 and 25 April 2026. Data on vaccination status, sociodemographic characteristics, feeding practices, nutritional status, clinical symptoms, and complications were collected through caregiver interviews and hospital records. Adjusted odds ratios (AOR) with 95% confidence intervals (CI) were estimated; p < 0.05 was considered statistically significant. Among enrolled children, 74.6% were unvaccinated, 18.8% were partially vaccinated, and only 6.5% were fully vaccinated. In the multivariable model, age below 9 months (aOR 0.09, 95% CI 0.03–0.268, p < 0.001) was independently associated with lower odds of vaccination, while household income at or above the median (aOR 3.983, 95% CI 1.8–8.813, p = 0.004) was associated with higher odds. Complications developed in 31.1% of cases, with respiratory involvement being most common. Absence of exclusive breastfeeding (aOR 2.336, 95% CI 1.027–5.313, p = 0.043) and presenting with exactly three symptoms at admission (aOR 3.106, 95% CI 1.274–7.572, p = 0.013) were independently associated with complications. Unvaccinated children had markedly higher odds of complications than vaccinated children (aOR 5.729, 95% CI: 2.363–13.889, p < 0.001). The heavy burden of measles among unvaccinated children, shaped by socioeconomic disadvantage and suboptimal feeding practices, underscores the urgent need to restore immunization coverage and strengthen equitable health services in Bangladesh.
SN  - 1932-6203
ER  -