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Peer-reviewedCC BY-NC-SAPostepy w kardiologii interwencyjnej = Advances in interventional cardiology

Comparison of transcatheter aortic valve replacement performed in a hybrid operating room versus a catheterization laboratory

  1. 1Department of Cardiology, University Hospital of Toulouse, Toulouse, France

Abstract

Introduction: Transcatheter aortic valve replacement (TAVR) can be performed in a catheterization laboratory (cath lab) or in a hybrid operating room (hybrid OR).

Aim: The objective of this study was to compare the safety of patients undergoing TAVR in a hybrid OR with those undergoing TAVR in a cath lab.

Material and methods: The primary endpoint was a composite safety endpoint, which includes freedom from all-cause in-hospital mortality, stroke, major vascular complications (VARC ≥ 2), aortic regurgitation (grade ≥ 2), new pacemaker implantation, emergent surgery, annulus rupture, tamponade, or stent femoral implantation. The two secondary endpoints consisted of technical failure criteria and device failure criteria, at hospital discharge.

Results: A total of 286 patients were included, 143 undergoing TF TAVR in the cath lab and 143 in a hybrid OR. Regarding the safety primary endpoint, there was no significant difference between the groups: 75.3% in the cath lab group versus 71.1% in the hybrid OR group (p = 0.421). There was also no significant difference in the technical failure criteria (3.5% in the cath lab group versus 4.2% in the hybrid OR group; p = 0.758) and device failure criteria (20.6% in the cath lab group versus 17.6% in the hybrid OR group; p = 0.526).

Conclusions: Regarding the composite safety and efficacy endpoints, no statistically significant between-group differences were detected in this unadjusted single-center cohort between patients undergoing TF-TAVR in a cath lab and those treated in a hybrid OR. These data suggest that performing TF TAVR in the cath lab can achieve high safety and effectiveness outcomes.

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BibTeX
@article{canitrot2026comparison,
  title = {{Comparison of transcatheter aortic valve replacement performed in a hybrid operating room versus a catheterization laboratory}},
  author = {Ronan Canitrot and Vincent Bataille and Frédéric Bouisset and Francisco Campelo-Parada and Didier Carrié and Thibault Lhermusier and Clément Servoz},
  journal = {Postepy w kardiologii interwencyjnej = Advances in interventional cardiology},
  year = {2026},
  month = sep,
  doi = {10.5114/aic.2026.164554},
  url = {https://europepmc.org/article/PMC/PMC13721050},
  note = {CC BY-NC-SA},
}
RIS
TY  - JOUR
TI  - Comparison of transcatheter aortic valve replacement performed in a hybrid operating room versus a catheterization laboratory
AU  - Ronan Canitrot
AU  - Vincent Bataille
AU  - Frédéric Bouisset
AU  - Francisco Campelo-Parada
AU  - Didier Carrié
AU  - Thibault Lhermusier
AU  - Clément Servoz
PY  - 2026
DA  - 2026/09/01
JO  - Postepy w kardiologii interwencyjnej = Advances in interventional cardiology
DO  - 10.5114/aic.2026.164554
UR  - https://europepmc.org/article/PMC/PMC13721050
AB  - Introduction: Transcatheter aortic valve replacement (TAVR) can be performed in a catheterization laboratory (cath lab) or in a hybrid operating room (hybrid OR).  Aim: The objective of this study was to compare the safety of patients undergoing TAVR in a hybrid OR with those undergoing TAVR in a cath lab.  Material and methods: The primary endpoint was a composite safety endpoint, which includes freedom from all-cause in-hospital mortality, stroke, major vascular complications (VARC ≥ 2), aortic regurgitation (grade ≥ 2), new pacemaker implantation, emergent surgery, annulus rupture, tamponade, or stent femoral implantation. The two secondary endpoints consisted of technical failure criteria and device failure criteria, at hospital discharge.  Results: A total of 286 patients were included, 143 undergoing TF TAVR in the cath lab and 143 in a hybrid OR. Regarding the safety primary endpoint, there was no significant difference between the groups: 75.3% in the cath lab group versus 71.1% in the hybrid OR group (p = 0.421). There was also no significant difference in the technical failure criteria (3.5% in the cath lab group versus 4.2% in the hybrid OR group; p = 0.758) and device failure criteria (20.6% in the cath lab group versus 17.6% in the hybrid OR group; p = 0.526).  Conclusions: Regarding the composite safety and efficacy endpoints, no statistically significant between-group differences were detected in this unadjusted single-center cohort between patients undergoing TF-TAVR in a cath lab and those treated in a hybrid OR. These data suggest that performing TF TAVR in the cath lab can achieve high safety and effectiveness outcomes.
SN  - 1734-9338
SN  - 1897-4295
ER  -