Efficacy of balloon guide catheter in endovascular treatment according to occlusion location
- 1Department of Neurology, Sivas Numune Hospital, Ministry of Health , ,
- 2Department of Neurology, Faculty of Medicine, Eskisehir Osmangazi University , ,
Abstract
Background and purpose: The clinical and procedural benefits of balloon guide catheter (BGC) use during mechanical thrombectomy remain debated, and whether these associations vary by occlusion location is uncertain. We evaluated the association of BGC use with thrombectomy outcomes and examined potential effect modification by occlusion location.
Methods: We retrospectively analyzed 475 patients with anterior-circulation large-vessel occlusion undergoing mechanical thrombectomy (BGC, n =242; non-BGC, n =233). Procedural, angiographic, and clinical outcomes were compared between groups. Multivariable logistic regression models adjusted for age, sex, baseline NIHSS, collateral status, occlusion location, atrial fibrillation, hypertension, diabetes mellitus, and coronary artery disease. BGC × occlusion-location interactions were assessed using adjusted generalized linear models.
Results: BGC use was independently associated with higher odds of 90-day functional independence (mRS 0–2; adjusted OR [aOR], 1.61; 95% CI, 1.05–2.48; p =0.029) and lower odds of embolization to new territory (aOR, 0.53; 95% CI, 0.35–0.81; p =0.004). BGC use was also associated with higher odds of vasospasm (aOR, 1.68; 95% CI, 1.09–2.58; p =0.018), whereas associations with first-pass recanalization and hemorrhagic complications were not significant. No significant BGC × occlusion-location interaction was observed for any evaluated outcome (all P for interaction>0.05).
Conclusion: BGC use was independently associated with favorable 90-day functional outcome and reduced embolization to new territory, but with increased vasospasm. No evidence of effect modification by occlusion location was identified. These findings support potential overall benefits of BGC use while emphasizing that location-specific effects remain unproven and require prospective evaluation.
Related
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BibTeX
@article{adiyaman2026efficacy,
title = {{Efficacy of balloon guide catheter in endovascular treatment according to occlusion location}},
author = {Hicret Betul Adiyaman and Zehra Uysal Kocabaş and Ozlem Aykac and Atilla Ozcan Ozdemir},
journal = {Frontiers in neurology},
year = {2026},
month = sep,
doi = {10.3389/fneur.2026.1867575},
url = {https://europepmc.org/article/PMC/PMC13661195},
note = {CC BY},
}
RIS
TY - JOUR
TI - Efficacy of balloon guide catheter in endovascular treatment according to occlusion location
AU - Hicret Betul Adiyaman
AU - Zehra Uysal Kocabaş
AU - Ozlem Aykac
AU - Atilla Ozcan Ozdemir
PY - 2026
DA - 2026/09/30
JO - Frontiers in neurology
DO - 10.3389/fneur.2026.1867575
UR - https://europepmc.org/article/PMC/PMC13661195
AB - Background and purpose: The clinical and procedural benefits of balloon guide catheter (BGC) use during mechanical thrombectomy remain debated, and whether these associations vary by occlusion location is uncertain. We evaluated the association of BGC use with thrombectomy outcomes and examined potential effect modification by occlusion location. Methods: We retrospectively analyzed 475 patients with anterior-circulation large-vessel occlusion undergoing mechanical thrombectomy (BGC, n =242; non-BGC, n =233). Procedural, angiographic, and clinical outcomes were compared between groups. Multivariable logistic regression models adjusted for age, sex, baseline NIHSS, collateral status, occlusion location, atrial fibrillation, hypertension, diabetes mellitus, and coronary artery disease. BGC × occlusion-location interactions were assessed using adjusted generalized linear models. Results: BGC use was independently associated with higher odds of 90-day functional independence (mRS 0–2; adjusted OR [aOR], 1.61; 95% CI, 1.05–2.48; p =0.029) and lower odds of embolization to new territory (aOR, 0.53; 95% CI, 0.35–0.81; p =0.004). BGC use was also associated with higher odds of vasospasm (aOR, 1.68; 95% CI, 1.09–2.58; p =0.018), whereas associations with first-pass recanalization and hemorrhagic complications were not significant. No significant BGC × occlusion-location interaction was observed for any evaluated outcome (all P for interaction>0.05). Conclusion: BGC use was independently associated with favorable 90-day functional outcome and reduced embolization to new territory, but with increased vasospasm. No evidence of effect modification by occlusion location was identified. These findings support potential overall benefits of BGC use while emphasizing that location-specific effects remain unproven and require prospective evaluation.
SN - 1664-2295
ER -