Acute Macular Neuroretinopathy after Intravitreal Ozurdex Injection in a Patient with Birdshot Chorioretinopathy: A Case Report.
- 1Department of Ophthalmology, National Treatment Centre Highland, Inverness, UK.
Abstract
Acute macular neuroretinopathy (AMN) is a rare retinal disorder linked to ischaemia of the deep capillary plexus. It has been reported after intravitreal injections, and this report describes an unreported temporal association between intravitreal Ozurdex and AMN. An HLA-A29-positive female with Birdshot chorioretinopathy and recurrent cystoid macular oedema, treated with prednisolone, mycophenolate mofetil, and adalimumab, presented with a paracentral ring scotoma within 24 h of a third Ozurdex injection. Multimodal imaging and 10-2 perimetry were performed and monitored over 6 months. Examination showed 6/15 vision and parafoveal pallor. OCT demonstrated foveal-sparing outer retinal hyper-reflectivity corresponding to the scotoma. Multimodal imaging outlined the area of retinal injury. Visual fields confirmed a ring scotoma. At 6 months, symptoms persisted and OCT showed photoreceptor loss. This case describes a previously unreported temporal association between intravitreal Ozurdex and AMN. Ophthalmologists should be aware of rare sight threatening events following intravitreal therapy including corticosteroids.
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BibTeX
@article{dhillon2026acute,
title = {{Acute Macular Neuroretinopathy after Intravitreal Ozurdex Injection in a Patient with Birdshot Chorioretinopathy: A Case Report.}},
author = {Niku Dhillon and David Knight},
journal = {Case reports in ophthalmology},
year = {2026},
month = sep,
doi = {10.1159/cop/acaag025},
url = {https://europepmc.org/article/MED/42953874},
note = {CC BY},
}
RIS
TY - JOUR
TI - Acute Macular Neuroretinopathy after Intravitreal Ozurdex Injection in a Patient with Birdshot Chorioretinopathy: A Case Report.
AU - Niku Dhillon
AU - David Knight
PY - 2026
DA - 2026/09/16
JO - Case reports in ophthalmology
DO - 10.1159/cop/acaag025
UR - https://europepmc.org/article/MED/42953874
AB - Acute macular neuroretinopathy (AMN) is a rare retinal disorder linked to ischaemia of the deep capillary plexus. It has been reported after intravitreal injections, and this report describes an unreported temporal association between intravitreal Ozurdex and AMN. An HLA-A29-positive female with Birdshot chorioretinopathy and recurrent cystoid macular oedema, treated with prednisolone, mycophenolate mofetil, and adalimumab, presented with a paracentral ring scotoma within 24 h of a third Ozurdex injection. Multimodal imaging and 10-2 perimetry were performed and monitored over 6 months. Examination showed 6/15 vision and parafoveal pallor. OCT demonstrated foveal-sparing outer retinal hyper-reflectivity corresponding to the scotoma. Multimodal imaging outlined the area of retinal injury. Visual fields confirmed a ring scotoma. At 6 months, symptoms persisted and OCT showed photoreceptor loss. This case describes a previously unreported temporal association between intravitreal Ozurdex and AMN. Ophthalmologists should be aware of rare sight threatening events following intravitreal therapy including corticosteroids.
SN - 1663-2699
ER -