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Peer-reviewedCC BY 4.0Case Reports in Critical Care

Pyomyositis in Northern California Following Provoked Deep Vein Thrombosis

  • Nicholas Sparr1,2
  • Avijit Baidwan1,2
  • Nathan C. Claydon1,2
  • Jessica McMichael3
  • Glenn Gookin1,2
  1. 1Medicine, Sierra Nevada Memorial Hospital, Grass Valley, California, USA
  2. 2Family Medicine, Sierra Nevada Family Medicine Residency Program, Grass Valley, California, USA
  3. 3Surgery, Sierra Nevada Memorial Hospital, Grass Valley, California, USA
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Abstract

Pyomyositis is an uncommon bacterial infection of the skeletal muscle, traditionally associated with tropical regions and immunocompromised hosts. We present a case of a 44‐year‐old immunocompetent female in Northern California who developed pyomyositis involving the vastus medialis, rectus femoris, and vastus lateralis. A drainable abscess was not initially demonstrated on computed tomography (CT) imaging, and diagnosis was delayed by findings of deep vein thrombosis (DVT) with septic pulmonary emboli in the setting of septic shock due to methicillin‐sensitive Staphylococcus aureus (MSSA) bacteremia. Two possible pathogenetic mechanisms were considered: either a provoked DVT from immobilization following recent lower extremity surgery served as a nidus for bacterial seeding, or alternatively, a superficial thigh abscess triggered a hypercoagulable state leading to DVT formation and subsequent bacterial seeding. In either scenario, muscle strain from impaired mobility rendered the tissues vulnerable to abscess formation. The patient required multiple surgical debridements and prolonged intravenous antibiotic therapy for successful treatment. This case reveals atypical pathogenetic mechanisms for pyomyositis and highlights the necessity for physicians to remain vigilant for this disease process that has demonstrated an increasing incidence rate in the United States, even in immunocompetent hosts and in temperate climates.

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Cite

BibTeXRIS
BibTeX
@article{sparr2026pyomyositis,
  title = {{Pyomyositis in Northern California Following Provoked Deep Vein Thrombosis}},
  author = {Nicholas Sparr and Avijit Baidwan and Nathan C. Claydon and Jessica McMichael and Glenn Gookin},
  journal = {Case Reports in Critical Care},
  year = {2026},
  month = jun,
  doi = {10.1155/crcc/8846829},
  url = {https://doi.org/10.1155/crcc/8846829},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Pyomyositis in Northern California Following Provoked Deep Vein Thrombosis
AU  - Nicholas Sparr
AU  - Avijit Baidwan
AU  - Nathan C. Claydon
AU  - Jessica McMichael
AU  - Glenn Gookin
PY  - 2026
DA  - 2026/06/02
JO  - Case Reports in Critical Care
DO  - 10.1155/crcc/8846829
UR  - https://doi.org/10.1155/crcc/8846829
AB  - Pyomyositis is an uncommon bacterial infection of the skeletal muscle, traditionally associated with tropical regions and immunocompromised hosts. We present a case of a 44‐year‐old immunocompetent female in Northern California who developed pyomyositis involving the vastus medialis, rectus femoris, and vastus lateralis. A drainable abscess was not initially demonstrated on computed tomography (CT) imaging, and diagnosis was delayed by findings of deep vein thrombosis (DVT) with septic pulmonary emboli in the setting of septic shock due to methicillin‐sensitive Staphylococcus aureus (MSSA) bacteremia. Two possible pathogenetic mechanisms were considered: either a provoked DVT from immobilization following recent lower extremity surgery served as a nidus for bacterial seeding, or alternatively, a superficial thigh abscess triggered a hypercoagulable state leading to DVT formation and subsequent bacterial seeding. In either scenario, muscle strain from impaired mobility rendered the tissues vulnerable to abscess formation. The patient required multiple surgical debridements and prolonged intravenous antibiotic therapy for successful treatment. This case reveals atypical pathogenetic mechanisms for pyomyositis and highlights the necessity for physicians to remain vigilant for this disease process that has demonstrated an increasing incidence rate in the United States, even in immunocompetent hosts and in temperate climates.
SN  - 2090-6420
SN  - 2090-6439
ER  -