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Peer-reviewedCC BY 4.0PLOS Biology

Turning a phage anti-defense weapon into an immunity trigger

  • Anna B. Adelstein1
  • Naama Aviram
  1. 1Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
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Abstract

Most bacterial immune systems raise an alarm when they sense a phage. A new study in PLOS Biology shows how type II Panoptes reverses this logic by maintaining a quiet signal and sensing infection through its sudden disappearance.

Most bacterial immune systems raise an alarm when they sense a phage. A new study in PLOS Biology shows how type II Panoptes reverses this logic by maintaining a quiet signal and sensing infection through its sudden disappearance

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Cite

BibTeXRIS
BibTeX
@article{adelstein2026turning,
  title = {{Turning a phage anti-defense weapon into an immunity trigger}},
  author = {Anna B. Adelstein and Naama Aviram},
  journal = {PLOS Biology},
  year = {2026},
  month = sep,
  doi = {10.1371/journal.pbio.3003978},
  url = {https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3003978},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Turning a phage anti-defense weapon into an immunity trigger
AU  - Anna B. Adelstein
AU  - Naama Aviram
PY  - 2026
DA  - 2026/09/16
JO  - PLOS Biology
DO  - 10.1371/journal.pbio.3003978
UR  - https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3003978
AB  - Most bacterial immune systems raise an alarm when they sense a phage. A new study in PLOS Biology shows how type II Panoptes reverses this logic by maintaining a quiet signal and sensing infection through its sudden disappearance.  Most bacterial immune systems raise an alarm when they sense a phage. A new study in PLOS Biology shows how type II Panoptes reverses this logic by maintaining a quiet signal and sensing infection through its sudden disappearance
SN  - 1545-7885
ER  -