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Peer-reviewedCC BYMicroorganisms

The Effects of a Multi-Strain Probiotic Formulation Containing Saffron Extract and Fructooligosaccharides on Anxiety, Depressive Symptoms, Inflammatory Markers, and BDNF: A Double-Blind, Randomized, Placebo-Controlled Pilot Study

  • Marina Demetriou1
  • Christos Theleritis1
  • Evangelos Alevyzakis1
  • Efstathios Laskos2
  • Nikolaos Siafakas3
  • Maroulla D. Nikolaki4
  • Ioulia K. Tsetis5
  • Vasiliki Efstathiou1
  • Nikolaos Smyrnis1
  • Panagiotis Ferentinos1
  • Konstantinos Triantafyllou6
  • Nikos C. Stefanis7
1 more authors
  • Emmanouil Rizos1
7 affiliations
  1. 1Second Department of Psychiatry, “Attikon” University General Hospital, National and Kapodistrian University of Athens, 12462 Athens, Greece; (M.D.); (C.T.); (E.A.); (V.E.); (N.S.); (P.F.)
  2. 2Department of Biochemistry and Microbiology, Athens Psychiatric Hospital ‘Dromokaition’, 12461 Athens, Greece;
  3. 3Clinical Microbiology Laboratory, “Attikon” University General Hospital, National and Kapodistrian University of Athens, 12462 Athens, Greece;
  4. 4Department of Nutrition and Dietetics, “Attikon” University General Hospital, National and Kapodistrian University of Athens, 12462 Athens, Greece;
  5. 5Uni-Pharma S.A., 14564 Athens, Greece;
  6. 6Hepatogastroenterology Unit, Second Department of Internal Medicine and Research Institute, “Attikon” University General Hospital, National and Kapodistrian University of Athens, 12462 Athens, Greece;
  7. 7First Department of Psychiatry, Eginition Hospital, School of Medicine, National and Kapodistrian University of Athens, 11528 Athens, Greece;
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Cite

BibTeXRIS
BibTeX
@article{demetriou2026effects,
  title = {{The Effects of a Multi-Strain Probiotic Formulation Containing Saffron Extract and Fructooligosaccharides on Anxiety, Depressive Symptoms, Inflammatory Markers, and BDNF: A Double-Blind, Randomized, Placebo-Controlled Pilot Study}},
  author = {Marina Demetriou and Christos Theleritis and Evangelos Alevyzakis and Efstathios Laskos and Nikolaos Siafakas and Maroulla D. Nikolaki and Ioulia K. Tsetis and Vasiliki Efstathiou and Nikolaos Smyrnis and Panagiotis Ferentinos and Konstantinos Triantafyllou and Nikos C. Stefanis and Emmanouil Rizos},
  journal = {Microorganisms},
  year = {2026},
  month = sep,
  url = {https://europepmc.org/article/PMC/PMC13707462},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - The Effects of a Multi-Strain Probiotic Formulation Containing Saffron Extract and Fructooligosaccharides on Anxiety, Depressive Symptoms, Inflammatory Markers, and BDNF: A Double-Blind, Randomized, Placebo-Controlled Pilot Study
AU  - Marina Demetriou
AU  - Christos Theleritis
AU  - Evangelos Alevyzakis
AU  - Efstathios Laskos
AU  - Nikolaos Siafakas
AU  - Maroulla D. Nikolaki
AU  - Ioulia K. Tsetis
AU  - Vasiliki Efstathiou
AU  - Nikolaos Smyrnis
AU  - Panagiotis Ferentinos
AU  - Konstantinos Triantafyllou
AU  - Nikos C. Stefanis
AU  - Emmanouil Rizos
PY  - 2026
DA  - 2026/09/25
JO  - Microorganisms
UR  - https://europepmc.org/article/PMC/PMC13707462
SN  - 2076-2607
ER  -