PreprintCC BYmedRxiv
Using Routine Ventilator Data to Visualize and Quantify Dynamic Compliance Trends Post-Surfactant Therapy in Preterm Infants: A Proof-of-Concept Study
- 1Toyama Prefectural Central Hospital
Abstract
Using routinely recorded ventilator data from 16 preterm infants with respiratory distress syndrome, dynamic compliance trajectories after surfactant administration were smoothed with a moving-median filter and characterized with a four-parameter logistic model; 10 infants showed sigmoidal improvement, and among 11 infants who received a second surfactant dose, 6 showed subsequent improvement, suggesting that this approach can visualize and quantify individual compliance recovery as a complementary tool to conventional clinical indicators.
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BibTeX
@misc{higashiyama2026using,
title = {{Using Routine Ventilator Data to Visualize and Quantify Dynamic Compliance Trends Post-Surfactant Therapy in Preterm Infants: A Proof-of-Concept Study}},
author = {H. Higashiyama},
howpublished = {medRxiv},
year = {2026},
month = sep,
doi = {10.64898/2026.09.10.26362806},
url = {https://www.medrxiv.org/content/10.64898/2026.09.10.26362806v1},
note = {CC BY},
}
RIS
TY - UNPB
TI - Using Routine Ventilator Data to Visualize and Quantify Dynamic Compliance Trends Post-Surfactant Therapy in Preterm Infants: A Proof-of-Concept Study
AU - H. Higashiyama
PY - 2026
DA - 2026/09/10
PB - medRxiv
DO - 10.64898/2026.09.10.26362806
UR - https://www.medrxiv.org/content/10.64898/2026.09.10.26362806v1
AB - Using routinely recorded ventilator data from 16 preterm infants with respiratory distress syndrome, dynamic compliance trajectories after surfactant administration were smoothed with a moving-median filter and characterized with a four-parameter logistic model; 10 infants showed sigmoidal improvement, and among 11 infants who received a second surfactant dose, 6 showed subsequent improvement, suggesting that this approach can visualize and quantify individual compliance recovery as a complementary tool to conventional clinical indicators.
ER -