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Peer-reviewedCC BY 4.0Cureus

The Role of a 1064-nm Picosecond Laser in Treating Prolonged Bruising Secondary to Liquid Polycaprolactone Injection

  1. 1Dermatology, Soliman Fakeeh Hospital, Riyadh, SAU

Abstract

Liquid-form polycaprolactone (PCL) is an increasingly utilized dermal biostimulator in aesthetic dermatology. We report the case of a 72-year-old man who developed persistent infraorbital bruising following bilateral tear trough injection of liquid PCL. Owing to bruising persisting over six weeks, the patient underwent four weekly sessions of long-pulsed 1064-nm Nd laser therapy with minimal improvement. Subsequently, treatment with a 1064-nm picosecond laser was initiated, followed by resolution of the bruising after two sessions. To our knowledge, this represents the eighth reported case of prolonged bruising after liquid PCL injection and the sixth involving the tear trough region. We hypothesize that sequestration of hemoglobin degradation products within the PCL scaffold may contribute to prolonged bruising. Picosecond laser therapy was associated with clinical improvement in this patient and may represent a potentially useful therapeutic approach for this uncommon complication; however, its efficacy, optimal parameters, mechanism of action, and safety require confirmation in additional patients and controlled studies.

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BibTeX
@article{saleh2026role,
  title = {{The Role of a 1064-nm Picosecond Laser in Treating Prolonged Bruising Secondary to Liquid Polycaprolactone Injection}},
  author = {Zenus Saleh},
  journal = {Cureus},
  year = {2026},
  month = oct,
  doi = {10.7759/cureus.117667},
  url = {https://doi.org/10.7759/cureus.117667},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - The Role of a 1064-nm Picosecond Laser in Treating Prolonged Bruising Secondary to Liquid Polycaprolactone Injection
AU  - Zenus Saleh
PY  - 2026
DA  - 2026/10/09
JO  - Cureus
DO  - 10.7759/cureus.117667
UR  - https://doi.org/10.7759/cureus.117667
AB  - Liquid-form polycaprolactone (PCL) is an increasingly utilized dermal biostimulator in aesthetic dermatology. We report the case of a 72-year-old man who developed persistent infraorbital bruising following bilateral tear trough injection of liquid PCL. Owing to bruising persisting over six weeks, the patient underwent four weekly sessions of long-pulsed 1064-nm Nd laser therapy with minimal improvement. Subsequently, treatment with a 1064-nm picosecond laser was initiated, followed by resolution of the bruising after two sessions. To our knowledge, this represents the eighth reported case of prolonged bruising after liquid PCL injection and the sixth involving the tear trough region. We hypothesize that sequestration of hemoglobin degradation products within the PCL scaffold may contribute to prolonged bruising. Picosecond laser therapy was associated with clinical improvement in this patient and may represent a potentially useful therapeutic approach for this uncommon complication; however, its efficacy, optimal parameters, mechanism of action, and safety require confirmation in additional patients and controlled studies.
SN  - 2168-8184
ER  -