Clinical Applicability of an Intrarenal Venous Flow Analysis for the Diagnosis of Impaired 2 Hemodynamics regardless of the Chronic Kidney Disease Stage
Abstract
). The IRVF patterns were categorized as either continuous or discontinuous.Methods Hemodynamic parameters assessed using right heart catheterization included the mean right atrial pressure (mRAP), mean pulmonary artery pressure (mPAP), mean pulmonary artery wedge pressure (mPAWP), and mean inferior vena cava pressure (mIVCP). The associations between IRVF patterns and hemodynamic parameters were analyzed, and a multivariate logistic regression analysis was performed to identify the independent predictors of discontinuous IRVF.Results Discontinuous IRVF was observed in 65 patients (29%) and it was more frequent in those with lower eGFR. Across all CKD stages, patients with discontinuous IRVF had significantly higher mRAP, mPAP, and mPAWP than those with continuous IRVF. A multivariate analysis identified mRAP, mPAP, and moderate or greater tricuspid regurgitation as independent predictors of discontinuous IRVF.Conclusion An IRVF analysis may be a useful noninvasive method for detecting impaired hemodynamics in patients with CKD, including those undergoing dialysis.
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BibTeX
@article{kondo2026clinical,
title = {{Clinical Applicability of an Intrarenal Venous Flow Analysis for the Diagnosis of Impaired 2 Hemodynamics regardless of the Chronic Kidney Disease Stage}},
author = {Kengo Kondo and Tatsuya Nishikawa and Ayano Imai and Rie Miyake and Kento Ota and Hibiki Kadohara and Yuya Ohga and Motohiro Shingu and Yuto Osumi and Kenta Ishibashi and Toshimitsu Ishii and Mana Hiraishi and Mitsuo Kinugasa and Yasutaka Hirayama and Toshio Shimokawa and Koichi Tamita and Yuriko Yonekura},
journal = {Internal Medicine},
year = {2026},
month = aug,
doi = {10.2169/internalmedicine.7559-26},
url = {https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7559-26/_article},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Clinical Applicability of an Intrarenal Venous Flow Analysis for the Diagnosis of Impaired 2 Hemodynamics regardless of the Chronic Kidney Disease Stage
AU - Kengo Kondo
AU - Tatsuya Nishikawa
AU - Ayano Imai
AU - Rie Miyake
AU - Kento Ota
AU - Hibiki Kadohara
AU - Yuya Ohga
AU - Motohiro Shingu
AU - Yuto Osumi
AU - Kenta Ishibashi
AU - Toshimitsu Ishii
AU - Mana Hiraishi
AU - Mitsuo Kinugasa
AU - Yasutaka Hirayama
AU - Toshio Shimokawa
AU - Koichi Tamita
AU - Yuriko Yonekura
PY - 2026
DA - 2026/08/19
JO - Internal Medicine
DO - 10.2169/internalmedicine.7559-26
UR - https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7559-26/_article
AB - ). The IRVF patterns were categorized as either continuous or discontinuous.Methods Hemodynamic parameters assessed using right heart catheterization included the mean right atrial pressure (mRAP), mean pulmonary artery pressure (mPAP), mean pulmonary artery wedge pressure (mPAWP), and mean inferior vena cava pressure (mIVCP). The associations between IRVF patterns and hemodynamic parameters were analyzed, and a multivariate logistic regression analysis was performed to identify the independent predictors of discontinuous IRVF.Results Discontinuous IRVF was observed in 65 patients (29%) and it was more frequent in those with lower eGFR. Across all CKD stages, patients with discontinuous IRVF had significantly higher mRAP, mPAP, and mPAWP than those with continuous IRVF. A multivariate analysis identified mRAP, mPAP, and moderate or greater tricuspid regurgitation as independent predictors of discontinuous IRVF.Conclusion An IRVF analysis may be a useful noninvasive method for detecting impaired hemodynamics in patients with CKD, including those undergoing dialysis.
SN - 1349-7235
SN - 0918-2918
ER -