Case Report: Selective PRP application during staged MEEK-based reconstruction of extensive deep burns
- 1Department of Burn and Plastic Surgery, Jilin Chemical Hospital, Genertec Baoshihua Medical, Jilin City, Jilin Province, China
Abstract
Background: Staged grafting may be required after extensive deep burns when donor skin is limited. We describe the clinical course of three patients treated with selective platelet-rich plasma (PRP) application during MEEK-based reconstruction.
Case description: Three men with 21%, 45%, and 40% total body surface area (TBSA) burns underwent staged debridement and autologous grafting. PRP was administered during two of two, three of four, and one of three burn-wound operations, respectively. Approximate, chart-recorded graft-take estimates ranged from 80% to 95% across procedures, including procedures without PRP; these estimates were not obtained using a documented standardized measurement method. At discharge, Patient 1 had complete epithelialization, whereas Patients 2 and 3 had small residual wounds. At photographic follow-up approximately 2.5–3.5 months after discharge, no recurrent deep burn wounds or clinically documented infection were noted; Patient 1 had superficial scar ulcerations. Retrospectively reported Vancouver Scar Scale (VSS) scores were 8, 9, and 10, with incomplete documentation of the original assessment method.
Conclusion: The cases describe an individualized staged-reconstruction pathway incorporating selectively applied PRP. They do not establish a separate effect of PRP on graft take, infection, healing, or scar outcomes.
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BibTeX
@article{tian2026case,
title = {{Case Report: Selective PRP application during staged MEEK-based reconstruction of extensive deep burns}},
author = {Baoxiang Tian and Xue Ren and Hailong Lin and Yang Liu and Chunlin Wei and Dujuan Liu and Fucheng Zhang and Xiong Yang},
journal = {Frontiers in Surgery},
year = {2026},
month = oct,
doi = {10.3389/fsurg.2026.1921231},
url = {https://doi.org/10.3389/fsurg.2026.1921231},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Case Report: Selective PRP application during staged MEEK-based reconstruction of extensive deep burns
AU - Baoxiang Tian
AU - Xue Ren
AU - Hailong Lin
AU - Yang Liu
AU - Chunlin Wei
AU - Dujuan Liu
AU - Fucheng Zhang
AU - Xiong Yang
PY - 2026
DA - 2026/10/21
JO - Frontiers in Surgery
DO - 10.3389/fsurg.2026.1921231
UR - https://doi.org/10.3389/fsurg.2026.1921231
AB - Background: Staged grafting may be required after extensive deep burns when donor skin is limited. We describe the clinical course of three patients treated with selective platelet-rich plasma (PRP) application during MEEK-based reconstruction. Case description: Three men with 21%, 45%, and 40% total body surface area (TBSA) burns underwent staged debridement and autologous grafting. PRP was administered during two of two, three of four, and one of three burn-wound operations, respectively. Approximate, chart-recorded graft-take estimates ranged from 80% to 95% across procedures, including procedures without PRP; these estimates were not obtained using a documented standardized measurement method. At discharge, Patient 1 had complete epithelialization, whereas Patients 2 and 3 had small residual wounds. At photographic follow-up approximately 2.5–3.5 months after discharge, no recurrent deep burn wounds or clinically documented infection were noted; Patient 1 had superficial scar ulcerations. Retrospectively reported Vancouver Scar Scale (VSS) scores were 8, 9, and 10, with incomplete documentation of the original assessment method. Conclusion: The cases describe an individualized staged-reconstruction pathway incorporating selectively applied PRP. They do not establish a separate effect of PRP on graft take, infection, healing, or scar outcomes.
SN - 2296-875X
ER -