Channel-Focused Modified TURP for Post-Radiation Bladder Outlet Obstruction: A Case Series
- 1Department of Urology, Severance Hospital, College of Medicine, Yonsei University, Seoul 03722, Republic of Korea
Abstract
Background/Objectives: Bladder outlet obstruction (BOO) after prostate radiotherapy is surgically challenging because of radiation-induced tissue changes and functional complications. We evaluated the efficacy and safety of channel-focused modified transurethral resection of the prostate (RadTURP) for post-radiation BOO. Methods: This retrospective case series included 11 patients who underwent RadTURP for post-radiation BOO between 2014 and 2025. Outcomes included symptom scores, voiding parameters, and postoperative complications. Pre–post changes were assessed using the Wilcoxon signed-rank test. Results: Median age was 75 years and median follow-up was 29 months. The median resection proportion was 24%. IPSS improved from 27 to 10 (p = 0.003), QoL from 5 to 3 (p = 0.007), OABSS from 12 to 6 (p = 0.016), Qmax from 6 to 17 mL/s (p = 0.006), and PVR from 59 to 0 mL (p = 0.047). De novo urinary incontinence occurred in four patients (36.4%), including two (18.2%) with persistent stress urinary incontinence requiring artificial urinary sphincter implantation. Among six patients undergoing symptom-driven postoperative cystoscopy, five (83.3%) had stone/calcification-related findings requiring energy-free endoscopic removal. One patient (9.1%) developed a urethral stricture requiring repeated dilation. Conclusions: In this small case series, channel-focused RadTURP was associated with improved urinary symptoms and voiding function after prostate radiotherapy. However, de novo urinary incontinence occurred in 36.4% of patients, highlighting an important postoperative safety concern for patient counseling and selection. Larger studies are needed to define durability and safety.
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BibTeX
@article{lee2026channelfocused,
title = {{Channel-Focused Modified TURP for Post-Radiation Bladder Outlet Obstruction: A Case Series}},
author = {Jeong Hyun Lee and Jang Hwan Kim and Kyung Tak Oh},
journal = {Journal of Clinical Medicine},
year = {2026},
month = oct,
doi = {10.3390/jcm15208168},
url = {https://www.mdpi.com/2077-0383/15/20/8168},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Channel-Focused Modified TURP for Post-Radiation Bladder Outlet Obstruction: A Case Series
AU - Jeong Hyun Lee
AU - Jang Hwan Kim
AU - Kyung Tak Oh
PY - 2026
DA - 2026/10/20
JO - Journal of Clinical Medicine
DO - 10.3390/jcm15208168
UR - https://www.mdpi.com/2077-0383/15/20/8168
AB - Background/Objectives: Bladder outlet obstruction (BOO) after prostate radiotherapy is surgically challenging because of radiation-induced tissue changes and functional complications. We evaluated the efficacy and safety of channel-focused modified transurethral resection of the prostate (RadTURP) for post-radiation BOO. Methods: This retrospective case series included 11 patients who underwent RadTURP for post-radiation BOO between 2014 and 2025. Outcomes included symptom scores, voiding parameters, and postoperative complications. Pre–post changes were assessed using the Wilcoxon signed-rank test. Results: Median age was 75 years and median follow-up was 29 months. The median resection proportion was 24%. IPSS improved from 27 to 10 (p = 0.003), QoL from 5 to 3 (p = 0.007), OABSS from 12 to 6 (p = 0.016), Qmax from 6 to 17 mL/s (p = 0.006), and PVR from 59 to 0 mL (p = 0.047). De novo urinary incontinence occurred in four patients (36.4%), including two (18.2%) with persistent stress urinary incontinence requiring artificial urinary sphincter implantation. Among six patients undergoing symptom-driven postoperative cystoscopy, five (83.3%) had stone/calcification-related findings requiring energy-free endoscopic removal. One patient (9.1%) developed a urethral stricture requiring repeated dilation. Conclusions: In this small case series, channel-focused RadTURP was associated with improved urinary symptoms and voiding function after prostate radiotherapy. However, de novo urinary incontinence occurred in 36.4% of patients, highlighting an important postoperative safety concern for patient counseling and selection. Larger studies are needed to define durability and safety.
SN - 2077-0383
ER -