Peer-reviewedCC BYClinical case reports23 Oct 2026

Possible Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections (PANDAS) Presenting in Late Adolescence and Early Adulthood: A Case Series.

Tariq A Madani¹
Fahd S Alsallum¹
Ola H Abudaowd¹
Salman T Madani¹

¹Division of Infectious Diseases, Department of Medicine, Faculty of Medicine King Abdulaziz University, and King Abdulaziz University Hospital Jeddah Saudi Arabia.

Abstract

PANDAS-like syndromes may rarely occur beyond childhood. Although these patients may meet criteria for PANS, recognizing a possible streptococcal-triggered subgroup remains important for diagnosis, future biomarker discovery, and refinement of disease classification. Clinicians should consider post-infectious autoimmune neuropsychiatric syndromes in older patients with abrupt-onset OCD or tics following pharyngeal illness.

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BibTeX RIS

BibTeX

@article{madani2026possible,
  title = {{Possible Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections (PANDAS) Presenting in Late Adolescence and Early Adulthood: A Case Series.}},
  author = {Tariq A Madani and Fahd S Alsallum and Ola H Abudaowd and Salman T Madani},
  journal = {Clinical case reports},
  year = {2026},
  month = oct,
  doi = {10.1002/ccr3.73768},
  url = {https://europepmc.org/article/MED/42921162},
  note = {CC BY},
}

RIS

TY  - JOUR
TI  - Possible Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections (PANDAS) Presenting in Late Adolescence and Early Adulthood: A Case Series.
AU  - Tariq A Madani
AU  - Fahd S Alsallum
AU  - Ola H Abudaowd
AU  - Salman T Madani
PY  - 2026
DA  - 2026/10/23
JO  - Clinical case reports
DO  - 10.1002/ccr3.73768
UR  - https://europepmc.org/article/MED/42921162
AB  - PANDAS-like syndromes may rarely occur beyond childhood. Although these patients may meet criteria for PANS, recognizing a possible streptococcal-triggered subgroup remains important for diagnosis, future biomarker discovery, and refinement of disease classification. Clinicians should consider post-infectious autoimmune neuropsychiatric syndromes in older patients with abrupt-onset OCD or tics following pharyngeal illness.
SN  - 2050-0904
ER  -

Abstract

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