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Peer-reviewedCC BYAddiction science & clinical practice

"I really can't imagine anything that could've been more easy": patient perspectives on low-threshold peer-facilitated telemedicine hepatitis C treatment for people who use drugs.

5 affiliations
  1. 1Division of General Internal Medicine & Geriatrics, Section of Addiction Medicine, Department of Medicine, Oregon Health & Science University, Portland, OR, USA. [email protected].
  2. 2Comagine Health, OR, Portland, USA.
  3. 3Division of General Internal Medicine & Geriatrics, Section of Addiction Medicine, Department of Medicine, Oregon Health & Science University, Portland, OR, USA.
  4. 4Oregon Health & Science University, Portland, OR, USA.
  5. 5Division of General Internal Medicine & Geriatrics, Department of Medicine, Oregon Health & Science University, Portland, OR, USA.

Abstract

Background

Injection drug use among nonurban people has fueled sharp rises in Hepatitis C (HCV) infections. Innovative treatment models are needed that circumvent healthcare system barriers for people who use drugs (PWUD), particularly in rural areas. The Oregon HOPE TeleHCV study randomized PWUD living with HCV in rural Oregon to peer-facilitated and streamlined telemedicine HCV treatment (Peer TeleHCV) versus enhanced usual care (EUC) and assessed sustained virologic response at 12 weeks post treatment (SVR12). Peer Support Specialists (peers) conducted HCV screening in the community, facilitated pretreatment evaluation and linkage to telemedicine HCV treatment clinicians, and supported participants in HCV medication adherence. A qualitative investigation queried patients about their experiences with the implementation of the model.Methods

This qualitative study explored patient experiences with the Peer TeleHCV model in rural Oregon. We conducted semi-structured interviews with 34 participants purposively sampled from a larger randomized trial comparing Peer TeleHCV with enhanced usual care. The qualitative team analyzed transcripts using a thematic analysis framework combining inductive and deductive coding.Results

Participants described the model as accessible, supportive, and low barrier. We identified three major themes: 1) Staff approach and values facilitated engagement in care; 2) Convenience and flexibility made care accessible, and 3) Support addressing needs helped overcome barriers to care.Conclusion

Findings highlight how community-based peers, integrated telemedicine, and flexible model design together reduce structural barriers to HCV care for rural PWUD. Adapting peer-facilitated telemedicine models can inform broader implementation of low-threshold, equitable approaches for substance use disorders and infectious disease treatment.

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BibTeX
@article{hoffman2026really,
  title = {{"I really can't imagine anything that could've been more easy": patient perspectives on low-threshold peer-facilitated telemedicine hepatitis C treatment for people who use drugs.}},
  author = {Kim Hoffman and Gillian Leichtling and Sarah Shin and Andrew Seaman and Tonhi Gailey and Hunter C Spencer and P Todd Korthuis},
  journal = {Addiction science \& clinical practice},
  year = {2026},
  month = jul,
  doi = {10.1186/s13722-026-00704-z},
  url = {https://europepmc.org/article/MED/42897587},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - "I really can't imagine anything that could've been more easy": patient perspectives on low-threshold peer-facilitated telemedicine hepatitis C treatment for people who use drugs.
AU  - Kim Hoffman
AU  - Gillian Leichtling
AU  - Sarah Shin
AU  - Andrew Seaman
AU  - Tonhi Gailey
AU  - Hunter C Spencer
AU  - P Todd Korthuis
PY  - 2026
DA  - 2026/07/01
JO  - Addiction science & clinical practice
DO  - 10.1186/s13722-026-00704-z
UR  - https://europepmc.org/article/MED/42897587
AB  - Background  Injection drug use among nonurban people has fueled sharp rises in Hepatitis C (HCV) infections. Innovative treatment models are needed that circumvent healthcare system barriers for people who use drugs (PWUD), particularly in rural areas. The Oregon HOPE TeleHCV study randomized PWUD living with HCV in rural Oregon to peer-facilitated and streamlined telemedicine HCV treatment (Peer TeleHCV) versus enhanced usual care (EUC) and assessed sustained virologic response at 12 weeks post treatment (SVR12). Peer Support Specialists (peers) conducted HCV screening in the community, facilitated pretreatment evaluation and linkage to telemedicine HCV treatment clinicians, and supported participants in HCV medication adherence. A qualitative investigation queried patients about their experiences with the implementation of the model.Methods  This qualitative study explored patient experiences with the Peer TeleHCV model in rural Oregon. We conducted semi-structured interviews with 34 participants purposively sampled from a larger randomized trial comparing Peer TeleHCV with enhanced usual care. The qualitative team analyzed transcripts using a thematic analysis framework combining inductive and deductive coding.Results  Participants described the model as accessible, supportive, and low barrier. We identified three major themes: 1) Staff approach and values facilitated engagement in care; 2) Convenience and flexibility made care accessible, and 3) Support addressing needs helped overcome barriers to care.Conclusion  Findings highlight how community-based peers, integrated telemedicine, and flexible model design together reduce structural barriers to HCV care for rural PWUD. Adapting peer-facilitated telemedicine models can inform broader implementation of low-threshold, equitable approaches for substance use disorders and infectious disease treatment.
SN  - 1940-0632
SN  - 1940-0640
ER  -