Somatostatin Receptor Scintigraphy Aiding the Exclusion of Cardiac Sarcoidosis in a Patient with Duodenal Neuroendocrine Tumor who Developed Complete Atrioventricular Block
Abstract
Cardiac sarcoidosis is a major cause of complete atrioventricular block. Although fluorodeoxyglucose-positron emission tomography (FDG PET/CT) is valuable for the diagnosis, inadequate fasting may result in a physiological myocardial uptake, making interpretation difficult. Somatostatin receptor scintigraphy (SRS), which does not require fasting, has been reported to detect myocardial inflammation in patients with DCM. We herein report the case of a 72-year-old man who developed complete atrioventricular block after surgery for a duodenal neuroendocrine tumor. In this patient, FDG PET/CT showed a marked cardiac uptake, while SRS findings suggested a low likelihood of cardiac sarcoidosis. In patients with malignancies and cardiovascular diseases, SRS may be useful for excluding cardiac sarcoidosis.
Related
- Primary adrenal small cell neuroendocrine carcinoma in a patient with sarcoidosis and synchronous colon adenocarcinoma
- Advances in Somatostatin Receptor-Targeting Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumors: Biological Rationale, Combination Strategies, and Clinical Perspectives.
- Somatostatin Analogues Do Not Improve Survival in Grade 3 Gastroenteropancreatic Neuroendocrine Neoplasms: A Registry-Based Analysis with Ki-67 Stratification
- Incidental Popliteal Bursa Localization on I-131 Whole-Body Scintigraphy
- Diagnostic Concordance of Immediate Versus 1-Hour Technetium-99m Hydroxymethylene Diphosphonate Scintigraphy in Suspected Transthyretin Amyloid Cardiomyopathy
BibTeX
@article{kurokawa2026somatostatin,
title = {{Somatostatin Receptor Scintigraphy Aiding the Exclusion of Cardiac Sarcoidosis in a Patient with Duodenal Neuroendocrine Tumor who Developed Complete Atrioventricular Block}},
author = {Keisho Kurokawa and Akinori Higaki and Motohira Yoshida and Rikako Horie and Ryo Miyabe and Amane Otoi and Hiroshi Kawakami and Osamu Yamaguchi},
journal = {Internal Medicine},
year = {2026},
month = jul,
doi = {10.2169/internalmedicine.7166-26},
url = {https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7166-26/_article},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Somatostatin Receptor Scintigraphy Aiding the Exclusion of Cardiac Sarcoidosis in a Patient with Duodenal Neuroendocrine Tumor who Developed Complete Atrioventricular Block
AU - Keisho Kurokawa
AU - Akinori Higaki
AU - Motohira Yoshida
AU - Rikako Horie
AU - Ryo Miyabe
AU - Amane Otoi
AU - Hiroshi Kawakami
AU - Osamu Yamaguchi
PY - 2026
DA - 2026/07/11
JO - Internal Medicine
DO - 10.2169/internalmedicine.7166-26
UR - https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7166-26/_article
AB - Cardiac sarcoidosis is a major cause of complete atrioventricular block. Although fluorodeoxyglucose-positron emission tomography (FDG PET/CT) is valuable for the diagnosis, inadequate fasting may result in a physiological myocardial uptake, making interpretation difficult. Somatostatin receptor scintigraphy (SRS), which does not require fasting, has been reported to detect myocardial inflammation in patients with DCM. We herein report the case of a 72-year-old man who developed complete atrioventricular block after surgery for a duodenal neuroendocrine tumor. In this patient, FDG PET/CT showed a marked cardiac uptake, while SRS findings suggested a low likelihood of cardiac sarcoidosis. In patients with malignancies and cardiovascular diseases, SRS may be useful for excluding cardiac sarcoidosis.
SN - 1349-7235
SN - 0918-2918
ER -