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PreprintCC BY-NC-NDChemRxiv

Phytochemical Analysis and evaluation of the Antioxidant Activity of Cissus microdonta Planch.

  • Séraphine Kanto Aricia OLIARISOA1,2
  • Fanamperantsoa Andrianina RAMANAMIHAJA3,4
  • Faramalala Louise RABEMANDROSO1,2,3,4
  • Stanislas Fulgence LAHADSON3,4
  • Herilala Léa RASOANAIVO3,4
4 affiliations
  1. 1Mention Physique-chimie
  2. 2University of Toamasina
  3. 3Laboratoire de Chimie des Substances Naturelles et Chimie Organique Biologique (LCSN/COB
  4. 4University of Antananarivo
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Abstract

Cissus microdonta Planch. is traditionally used to treat jaundice in Madagascar. This study aimed to investigate the phytochemical profile of Cissus microdonta stems and evaluate its antioxidant activity. Hexane (1.75%), ethyl acetate (3.74%), and ethanol (1.67%) extracts of the plant stems were obtained by maceration. Phytochemical screening was performed. The antioxidant activity of the plant was evaluated using the DPPH assay. Compounds from the active extracts were isolated using liquid chromatography on silica gel and identified via spectroscopic analysis. The presence of alkaloids, leucoanthocyanins, saponins, triterpenes, saturated sterols, and leucoanthocyanidins was established. The evaluation of the antioxidant activity of the ethanolic extract of the plant revealed significant free-radical-scavenging capacity. One compound was isolated from the active ethyl acetate extract and identified as ursolic acid. This research has enhanced the understanding of the phytochemical profile and biological properties of Cissus microdonta Planch., suggesting that the plant may be a potential source of natural antioxidants.

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Cite

BibTeXRIS
BibTeX
@misc{oliarisoa2026phytochemical,
  title = {{Phytochemical Analysis and evaluation of the Antioxidant Activity of Cissus microdonta Planch.}},
  author = {Séraphine Kanto Aricia OLIARISOA and Fanamperantsoa Andrianina RAMANAMIHAJA and Faramalala Louise RABEMANDROSO and Stanislas Fulgence LAHADSON and Herilala Léa RASOANAIVO},
  howpublished = {ChemRxiv},
  year = {2026},
  month = oct,
  doi = {10.26434/chemrxiv.15010107/v1},
  url = {https://chemrxiv.org/doi/full/10.26434/chemrxiv.15010107/v1},
  note = {CC BY-NC-ND},
}
RIS
TY  - UNPB
TI  - Phytochemical Analysis and evaluation of the Antioxidant Activity of Cissus microdonta Planch.
AU  - Séraphine Kanto Aricia OLIARISOA
AU  - Fanamperantsoa Andrianina RAMANAMIHAJA
AU  - Faramalala Louise RABEMANDROSO
AU  - Stanislas Fulgence LAHADSON
AU  - Herilala Léa RASOANAIVO
PY  - 2026
DA  - 2026/10/08
PB  - ChemRxiv
DO  - 10.26434/chemrxiv.15010107/v1
UR  - https://chemrxiv.org/doi/full/10.26434/chemrxiv.15010107/v1
AB  - Cissus microdonta Planch. is traditionally used to treat jaundice in Madagascar. This study aimed to investigate the phytochemical profile of Cissus microdonta stems and evaluate its antioxidant activity. Hexane (1.75%), ethyl acetate (3.74%), and ethanol (1.67%) extracts of the plant stems were obtained by maceration. Phytochemical screening was performed. The antioxidant activity of the plant was evaluated using the DPPH assay. Compounds from the active extracts were isolated using liquid chromatography on silica gel and identified via spectroscopic analysis. The presence of alkaloids, leucoanthocyanins, saponins, triterpenes, saturated sterols, and leucoanthocyanidins was established. The evaluation of the antioxidant activity of the ethanolic extract of the plant revealed significant free-radical-scavenging capacity. One compound was isolated from the active ethyl acetate extract and identified as ursolic acid. This research has enhanced the understanding of the phytochemical profile and biological properties of Cissus microdonta Planch., suggesting that the plant may be a potential source of natural antioxidants.
ER  -