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Peer-reviewedCC BY 4.0The Journal of Laryngology and Otology

Pro-inflammatory diet association with sudden sensorineural hearing loss: a case-control study

  • Kadir Sinasi Bulut1
  • Basak Yalciner2
  • Burak Celik1
  • Esra Zeynep Karakus3
  • Erva Nur Topaloglu3
  1. 1Otolaryngology, Head and Neck Surgery, Ankara Yildirim Beyazit University, Türkiye
  2. 2Otolaryngology, Head and Neck Surgery, Medical Park Hospitals Group, Türkiye
  3. 3Otolaryngology, Head and Neck Surgery, Ministry of Health Ankara City Hospital, Türkiye
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Abstract

Objectives: This study investigated whether the inflammatory potential of diet, assessed by the Dietary Inflammatory Index, is associated with sudden sensorineural hearing loss by comparing patients with sudden sensorineural hearing loss and healthy controls.

Methods: This retrospective case–control study included 30 patients with sudden sensorineural hearing loss and 32 matched controls. Dietary intake in the preceding 12 months was assessed by food frequency questionnaire, and Dietary Inflammatory Index scores were calculated. Between-group comparisons and receiver operating characteristics analysis were performed.

Results: Mean Dietary Inflammatory Index score was significantly higher in the sudden sensorineural hearing loss group than in controls (2.27 ± 1.21 vs. 1.46 ± 1.14; p = 0.01). Patients with sudden sensorineural hearing loss had higher energy, saturated fat and cholesterol intake, while omega-3 fatty acid and fibre intake were lower (p < 0.05). Dietary Inflammatory Index scores demonstrated moderate discriminative ability for sudden sensorineural hearing loss (area under the curve = 0.690; p = 0.005).

Conclusion: A pro-inflammatory dietary profile may be associated with increased sudden sensorineural hearing loss risk and may contribute to understanding modifiable risk factors.

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Cite

BibTeXRIS
BibTeX
@article{bulut2026proinflammatory,
  title = {{Pro-inflammatory diet association with sudden sensorineural hearing loss: a case-control study}},
  author = {Kadir Sinasi Bulut and Basak Yalciner and Burak Celik and Esra Zeynep Karakus and Erva Nur Topaloglu},
  journal = {The Journal of Laryngology and Otology},
  year = {2026},
  month = nov,
  doi = {10.1017/s0022215126105416},
  url = {https://doi.org/10.1017/s0022215126105416},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Pro-inflammatory diet association with sudden sensorineural hearing loss: a case-control study
AU  - Kadir Sinasi Bulut
AU  - Basak Yalciner
AU  - Burak Celik
AU  - Esra Zeynep Karakus
AU  - Erva Nur Topaloglu
PY  - 2026
DA  - 2026/11/06
JO  - The Journal of Laryngology and Otology
DO  - 10.1017/s0022215126105416
UR  - https://doi.org/10.1017/s0022215126105416
AB  - Objectives: This study investigated whether the inflammatory potential of diet, assessed by the Dietary Inflammatory Index, is associated with sudden sensorineural hearing loss by comparing patients with sudden sensorineural hearing loss and healthy controls.  Methods: This retrospective case–control study included 30 patients with sudden sensorineural hearing loss and 32 matched controls. Dietary intake in the preceding 12 months was assessed by food frequency questionnaire, and Dietary Inflammatory Index scores were calculated. Between-group comparisons and receiver operating characteristics analysis were performed.  Results: Mean Dietary Inflammatory Index score was significantly higher in the sudden sensorineural hearing loss group than in controls (2.27 ± 1.21 vs. 1.46 ± 1.14; p = 0.01). Patients with sudden sensorineural hearing loss had higher energy, saturated fat and cholesterol intake, while omega-3 fatty acid and fibre intake were lower (p < 0.05). Dietary Inflammatory Index scores demonstrated moderate discriminative ability for sudden sensorineural hearing loss (area under the curve = 0.690; p = 0.005).  Conclusion: A pro-inflammatory dietary profile may be associated with increased sudden sensorineural hearing loss risk and may contribute to understanding modifiable risk factors.
SN  - 0022-2151
SN  - 1748-5460
ER  -